Table 2 Univariate and multivariate analyses of prognostic values of clinicopathologic features and CEP78 expression for overall survival of CRC patients
Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR (95 % CI) | P value | HR (95 % CI) | P value | |
Age (≤50 years vs. >50 years) | 0.994 (0.658–1.501) | 0.976 | ||
Gender (female vs. male) | 1.072 (0.719–1.597) | 0.733 | ||
Tumor size (≤4 cm vs. >4 cm) | 2.125 (1.273–3.548) | 0.004 | 1.873 (1.095–3.323) | 0.022 |
Tumor differentiation (well vs. moderate vs. poor) | 0.214 (0.029–1.574) | 0.096 | ||
Depth of tumor (T1 + T2 vs. T3 + T4) | 4.881 (2.129–11.19) | <0.001 | 0.815 (0.450–1.477) | 0.500 |
Lymphatic metastasis (absent vs. present) | 3.714 (2.351–5.865) | <0.001 | 1.537 (0.830–2.847) | 0.172 |
Distant metastasis (absent vs. present) | 4.954 (3.283–7.475) | <0.001 | 2.744 (1.701–4.425) | <0.001 |
TNM stage (I + II vs. III + IV) | 7.373 (4.003–13.58) | <0.001 | 3.642 (1.492–8.894) | 0.005 |
CEP78 expression (low vs. high) | 0.520 (0.318–0.852) | 0.009 | 0.787 (0.475–1.305) | 0.354 |