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Table 1 Unadjusted outcomes at 3 years of acute myeloid leukemia (AML) patients with t(8;21) who achieved complete remission after 1–2 induction chemotherapy cycles

From: Low WT1 transcript levels at diagnosis predicted poor outcomes of acute myeloid leukemia patients with t(8;21) who received chemotherapy or allogeneic hematopoietic stem cell transplantation

Group

CIR rate

LFS rate

OS rate

Chemotherapy only

71% (63%–80%)

26% (15%–43%)

41% (25%–58%)

Auto-HSCT

8% (0%–71%)

85% (51%–96%)

92% (57%–99%)

Allo-HSCT

16% (10%–22%)

72% (56%–83%)

77% (61%–87%)

All cohorts

37% (25%–50%)

56% (45%–65%)

65% (54%–74%)

  1. CIR cumulative incidence of relapse, LFS leukemia-free survival, OS overall survival, allo-HSCT allogeneic hematopoietic stem cell transplantation, auto-HSCT autologous-hematopoietic stem cell transplantation