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Table 2 Univariate analysis of prognostic factors for DFS and CSS

From: Association of perioperative blood pressure with long-term survival in rectal cancer patients

Factor

DFS

CSS

3-year rate (%)

HR (95% CI)

P

3-year rate (%)

HR (95% CI)

P

Age

1.00 (0.99–1.02)

0.644

1.03 (1.01–1.06)

0.016

TNM stage, AJCC

 III

60.3

3.94 (1.95–7.99)

<0.001

79.7

5.24 (1.58–17.42)

0.007

 II

79.7

1.81 (0.82–4.01)

0.142

86.6

3.14 (0.88–11.24)

0.079

 I

84.4

1.00

 

94.7

1.00

 

Vascular invasion

 Positive

59.3

1.93 (1.10–3.39)

0.021

77.6

1.70 (0.71–4.07)

0.234

 Negative

73.7

1.00

 

86.7

1.00

 

Perineural invasion

 Positive

38.0

3.44 (1.98–5.98)

<0.001

73.8

2.45 (1.02–5.90)

0.046

 Negative

75.4

1.00

 

87.0

1.00

 

Preoperative CEA (ng/mL)

 >5

63.9

1.59 (1.00–2.52)

0.050

75.2

2.91 (1.48–5.71)

0.002

 0–5

77.2

1.00

 

92.2

1.00

 

Distance from anal verge (cm)

 5–12

75.5

0.59 (0.37–0.92)

0.021

89.3

0.47 (0.24–0.92)

0.028

 <5

69.3

1.00

 

82.0

1.00

 

Adjuvant treatment

 Yes

77.6

0.76 (0.49–1.18)

0.226

90.0

0.49 (0.25–0.94)

0.031

 No

67.2

1.00

 

80.7

1.00

 
  1. DFS disease-free survival, CSS cancer-specific survival, HR hazard ratio, CI confidence interval, SBP systolic blood pressure, BMI body mass index, BP blood pressure, AJCC American Joint Committee on Cancer, CEA carcinoembryonic antigen