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Table 2 ALN metastasis state of 567 patients detected by SLNB

From: Prospective study found that peripheral lymph node sampling reduced the false-negative rate of sentinel lymph node biopsy for breast cancer

SLN status ALN status Total
(+) (–)
(+) 172 (a) 0 (c) 172
(–) 19 (b) 376 (d) 395
Total 191 376 567
  1. For SLNB, the FNR was \(\left( {\rm{b}} \right)/\left( {{\rm{a + b}}} \right) = 19\;\left( {172{\rm{ + 19}}} \right) = 9.9\%\). Sensitivity was \(\left( {\rm{a}} \right)\left/\,( {{\rm{a + b}}} \right) = 172\;\left( {172{\rm{ + 19}}} \right) = 90.1\%\). Accuracy rate was \({{\left( {{\text{a}}{\mathbf{ + }}{\text{d}}} \right)} \mathord{\left/ {\vphantom {{\left( {{\text{a}}{\mathbf{ + }}{\text{d}}} \right)} {\left( {{\text{a}}\text{ + }{\text{b}}{\mathbf{ + }}{\text{c}}{\mathbf{ + }}{\text{d}}} \right) = {{\left( {172\text{ + 376}} \right)} \mathord{\left/ {\vphantom {{\left( {172\text{ + 376}} \right)} {\left( {172{\mathbf{ + }}19{\mathbf{ + }}0{\mathbf{ + }}376} \right)}}} \right. \kern-0pt} {\left( {172{\mathbf{ + }}19{\mathbf{ + }}0{\mathbf{ + }}376} \right)}} = 96.6\% }}} \right. \kern-0pt} {\left( {{\text{a}}\text{ + }{\text{b}}{\mathbf{ + }}{\text{c}}{\mathbf{ + }}{\text{d}}} \right) = {{\left( {172\text{ + 376}} \right)} \mathord{\left/ {\vphantom {{\left( {172\text{ + 376}} \right)} {\left( {172{\mathbf{ + }}19{\mathbf{ + }}0{\mathbf{ + }}376} \right)}}} \right. \kern-0pt} {\left( {172{\mathbf{ + }}19{\mathbf{ + }}0{\mathbf{ + }}376} \right)}} = 96.6\% }}\). Negative predictive value was \({{\left( {\text{d}} \right)} \mathord{\left/ {\vphantom {{\left( {\text{d}} \right)} {\left( {{\text{b}}{\mathbf{ + }}{\text{d}}} \right)}}} \right. \kern-0pt} {\left( {{\text{b}}{\mathbf{ + }}{\text{d}}} \right)}} = {{376} \mathord{\left/ {\vphantom {{376} {\left( {19{\mathbf{ + }}376} \right)}}} \right. \kern-0pt} {\left( {19{\mathbf{ + }}376} \right)}} = 95.2\%\)
  2. Abbreviations: ALN axillary lymph node, SLNB sentinel lymph node biopsy, SLN sentinel lymph node, FNR false-negative rate