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Table 4 Acute and late toxicities in the 46 NPC patients treated with 50 Gy radiotherapy plus hematoporphyrin derivative

From: Forty-six cases of nasopharyngeal carcinoma treated with 50 Gy radiotherapy plus hematoporphyrin derivative: 20 years of follow-up and outcomes from the Sun Yat-sen University Cancer Center

Toxicity Grade 0 Grade 1 Grade 2 Grade 3 Grade 4
Acute toxicities
 Skin (dermatitis) 0 32 (69.6) 8 (17.4) 6 (13.0) 0
 Mucositis 0 16 (34.8) 20 (43.5) 10 (21.7) 0
 Xerostomia 0 33 (71.7) 13 (28.3) 0 0
 Hearing loss 40 (87.0) 6 (13.0) 0 0 0
Late toxicitiesa
 Temporal lobe necrosis 42 (100) 0 0 0 0
 Cranial nerve palsy 42 (100) 0 0 0 0
 Optic nerve/chiasm injury 42 (100) 0 0 0 0
 Brainstem injury 42 (100) 0 0 0 0
 Hypopituitarism 42 (100) 0 0 0 0
 Hypothyroidism 42 (100) 0 0 0 0
 Trismus 35 (83.3) 7 (16.7) 0 0 0
 Neck fibrosis 36 (85.7) 6 (14.3) 0 0 0
 Xerostomia 3 (7.1) 38 (90.5) 1 (2.4) 0 0
 Hearing loss 5 (11.9) 35 (83.3) 2 (4.8) 0 0
  1. All values are presented as the numbers of patients followed by percentages in the parentheses
  2. a The 42 patients who were followed up for at least 10 years are included in the analysis of late toxicities