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Table 5 List of genes differentially expressed between the EGFR exon 19 deletion and exon 21 L858R mutation groups

From: Clinical outcomes of EGFR-TKI treatment and genetic heterogeneity in lung adenocarcinoma patients with EGFR mutations on exons 19 and 21

Gene Chromosome Reference base Mutated base Mutation frequency P valuea
EGFR 19 deletion Exon 21 L858R mutation Difference
EGFR 7 T 0 1 1 0.000
PARP1 1 A G 0.583 0.083 0.5 0.027
SPEN 1 T C 0.417 0 0.417 0.037
SPEN 1 A G 0.417 0 0.417 0.037
IGF1R 15 GGT G 0.417 0 0.417 0.037
NOS3 7 C G 0.583 0 0.583 0.005
KMT2D 12 G A 0.417 0 0.417 0.037
IGF1R 15 G A 0.417 0 0.417 0.037
SUFU 10 G A 0.583 0.083 0.5 0.027
EP300 22 T C 0.583 0.083 0.5 0.027
SPEN 1 A G 0.417 0 0.417 0.037
ACVR1B 12 C T 0.417 0 0.417 0.037
FLT1 13 T C 0.417 0 0.417 0.037
IGF1R 15 T C 0.417 0 0.417 0.037
RARA 17 C T 0.417 0 0.417 0.037
CSF1R 5 G A 0.417 0 0.417 0.037
ZC3HAV1 7 G A 0.417 0 0.417 0.037
NOS3 7 T G 0.5 0 0.5 0.014
ATG9B 7 G T 0.583 0.083 0.5 0.027
PARP1 1 C G 0.583 0.083 0.5 0.027
  1. aAnalyzed by using Fisher’s exact test