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Table 6 Association of RPMS1 SNP G155391A with the risk of NPC and other malignancies

From: A single nucleotide polymorphism in the Epstein-Barr virus genome is strongly associated with a high risk of nasopharyngeal carcinoma

Region Sample Source 155391G & 155391G/A 155391A OR P
Guangdong Healthy subjectsa TW 743 697 1  
  EBV-free tumor# TW 24 15 0.67 0.257
  NHL TB 8 5 0.67 0.582
  HL TB 7 3 0.46 0.345
  Lymphoma (NHL + HL) TB 15 8 0.57 0.213
  NPC TB 22 100 8.35˄ <0.001
Shandong Healthy subjectsa TW 578 34 1  
  EBVaGC TB 10 0 0 1.000
  NPC TB 23 13 Inf˅ 0.042
  1. NHL non-Hodgkin’s lymphoma, HL Hodgkin’s lymphoma, EBVaGC EBV-associated gastric carcinoma. Other abbreviations as in Tables 1 and 2
  2. aHealthy subjects from the discovery and replication stages were combined
  3. #EBV-free tumors included lung cancer, liver cancer, colorectal cancer, and pancreatic cancer, among others, which were not associated with EBV
  4. NHL included Burkitt’s and NK/T-cell lymphomas
  5. The frequency of RPMS1 SNP G155391A in healthy subjects from the same region was considered as a reference, with Fisher’s exact test performed
  6. ˄Lymphoma was considered as a reference
  7. ˅EBVaGC was considered as a reference