EBV variant
|
NPC
|
Healthy subjects
|
OR
|
95% CI
|
P value
|
---|
Data_GD1
|
155391G
|
28
|
132
|
1
| | |
G155391A
|
10
|
40
|
1.53
|
0.66–3.54
|
0.321
|
155391A
|
119
|
147
|
4.47
|
2.71–7.37
|
<0.001
|
P
†trend
| | | | |
<0.001
|
Data_GD2
|
155391G
|
28
|
125
|
1
| | |
G155391A
|
2
|
5
|
1.98
|
0.35–11.33
|
0.443
|
155391A
|
138
|
111
|
5.20
|
3.18–8.50
|
<0.001
|
P
†trend
| | | | |
<0.001
|
Data_GD3
|
155391G
|
99
|
357
|
1
| | |
G155391A
|
12
|
84
|
0.61
|
0.32–1.17
|
0.136
|
155391A
|
615
|
439
|
5.27
|
4.06–6.85
|
<0.001
|
P
†trend
| | | | |
<0.001
|
Data_SD
|
155391G
|
40
|
560
|
1
| | |
G155391A
|
0
|
18
|
0
|
0-Inf
|
0.987
|
155391A
|
18
|
34
|
7.52
|
3.69–15.32
|
<0.001
|
P
†trend
| | | | |
<0.001
|
Overalla
|
155391G
|
195
|
1174
|
1
| | |
G155391A
|
24
|
147
|
0.92
|
0.56–1.51
|
0.746
|
155391A
|
890
|
731
|
5.27
|
4.31–6.44
|
<0.001
|
P
†trend
| | | | |
<0.001
|
I
2
| | |
0
| | |
P
‡
| | | | |
0.710
|
-
OR odds ratio, 95% CI 95% confidence interval, Inf Infinity. Other abbreviations as in Tables 1 and 2
-
aDatasets integrated by meta-analysis
-
†
P
trend
Cochran-Armitage trend test in logistic regression analysis with adjustment for age and gender
-
‡
P heterogeneity test among the four datasets