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Table 4 Single nucleotide polymorphism (SNP) G155391A of RPMS1 and NPC risk

From: A single nucleotide polymorphism in the Epstein-Barr virus genome is strongly associated with a high risk of nasopharyngeal carcinoma

EBV variant NPC Healthy subjects OR 95% CI P value
Data_GD1
 155391G 28 132 1   
 G155391A 10 40 1.53 0.66–3.54 0.321
 155391A 119 147 4.47 2.71–7.37 <0.001
 P trend      <0.001
Data_GD2
 155391G 28 125 1   
 G155391A 2 5 1.98 0.35–11.33 0.443
 155391A 138 111 5.20 3.18–8.50 <0.001
 P trend      <0.001
Data_GD3
 155391G 99 357 1   
 G155391A 12 84 0.61 0.32–1.17 0.136
 155391A 615 439 5.27 4.06–6.85 <0.001
 P trend      <0.001
Data_SD
 155391G 40 560 1   
 G155391A 0 18 0 0-Inf 0.987
 155391A 18 34 7.52 3.69–15.32 <0.001
 P trend      <0.001
Overalla
 155391G 195 1174 1   
 G155391A 24 147 0.92 0.56–1.51 0.746
 155391A 890 731 5.27 4.31–6.44 <0.001
 P trend      <0.001
 I 2    0   
 P      0.710
  1. OR odds ratio, 95% CI 95% confidence interval, Inf Infinity. Other abbreviations as in Tables 1 and 2
  2. aDatasets integrated by meta-analysis
  3. P trend Cochran-Armitage trend test in logistic regression analysis with adjustment for age and gender
  4. P heterogeneity test among the four datasets