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Table 3 Univariate analysis for NSCLC patients with or without lymph node metastasis

From: Resectable left lower lobe non–small cell lung cancer with lymph node metastasis is related to unfavorable outcomes

Characteristic Node-negative patients (pN0) Node-positive patients (pN1–2)
HR (95% CI) P a HR (95% CI) P a
Sex (men vs. women) 0.617 (0.409–0.932) 0.022 1.085 (0.761–1.546) 0.653
Age (≤60 vs. >60 years) 1.367 (0.959–1.949) 0.084 1.004 (0.713–1.413) 0.983
Tumor location
 (Left vs. right lobe) 0.980 (0.679–1.414) 0.913 0.857 (0.611–1.202) 0.372
 (Upper vs. lower lobe) 1.505 (1.055–2.146) 0.024 1.132 (0.812–1.578) 0.465
 (Non-LLL vs. LLL) 1.554 (1.024–2.357) 0.038 1.528 (1.015–2.301) 0.042
T category (T1 vs. T2 vs. T3) 1.794 (1.284–2.507) 0.001 1.025 (0.694–1.515) 0.901
N category (N1 vs. N2) NA NA 1.049 (0.725–1.518) 0.801
Pathology (AC vs. SCC vs. others) 1.357 (1.066–1.727) 0.013 0.943 (0.732–1.213) 0.646
Histology grade (G1 vs. G2 vs. G3) 1.258 (0.994–1.592) 0.056 1.023 (0.797–1.314) 0.857
Tumor size (≤4 vs. >4 cm) 1.889 (1.324–2.696) <0.001 1.296 (0.924–1.816) 0.133
Pleural invasion (no vs. yes) 1.857 (1.064–3.242) 0.029 0.877 (0.505–1.525) 0.643
Resection (lobectomy vs. bilobectomy) 1.590 (0.774–3.265) 0.207 1.194 (0.699–2.040) 0.517
Adjuvant chemotherapy (yes vs. no) 1.490 (0.902–2.461) 0.120 1.241 (0.888–1.735) 0.207
  1. NA not available. Other abbreviations as in Table  2
  2. aCox proportional hazards regression analysis (forward stepwise)