Table 3 Univariate analysis for NSCLC patients with or without lymph node metastasis
Characteristic | Node-negative patients (pN0) | Node-positive patients (pN1–2) | ||
|---|---|---|---|---|
HR (95% CI) | P a | HR (95% CI) | P a | |
Sex (men vs. women) | 0.617 (0.409–0.932) | 0.022 | 1.085 (0.761–1.546) | 0.653 |
Age (≤60 vs. >60 years) | 1.367 (0.959–1.949) | 0.084 | 1.004 (0.713–1.413) | 0.983 |
Tumor location | ||||
(Left vs. right lobe) | 0.980 (0.679–1.414) | 0.913 | 0.857 (0.611–1.202) | 0.372 |
(Upper vs. lower lobe) | 1.505 (1.055–2.146) | 0.024 | 1.132 (0.812–1.578) | 0.465 |
(Non-LLL vs. LLL) | 1.554 (1.024–2.357) | 0.038 | 1.528 (1.015–2.301) | 0.042 |
T category (T1 vs. T2 vs. T3) | 1.794 (1.284–2.507) | 0.001 | 1.025 (0.694–1.515) | 0.901 |
N category (N1 vs. N2) | NA | NA | 1.049 (0.725–1.518) | 0.801 |
Pathology (AC vs. SCC vs. others) | 1.357 (1.066–1.727) | 0.013 | 0.943 (0.732–1.213) | 0.646 |
Histology grade (G1 vs. G2 vs. G3) | 1.258 (0.994–1.592) | 0.056 | 1.023 (0.797–1.314) | 0.857 |
Tumor size (≤4 vs. >4 cm) | 1.889 (1.324–2.696) | <0.001 | 1.296 (0.924–1.816) | 0.133 |
Pleural invasion (no vs. yes) | 1.857 (1.064–3.242) | 0.029 | 0.877 (0.505–1.525) | 0.643 |
Resection (lobectomy vs. bilobectomy) | 1.590 (0.774–3.265) | 0.207 | 1.194 (0.699–2.040) | 0.517 |
Adjuvant chemotherapy (yes vs. no) | 1.490 (0.902–2.461) | 0.120 | 1.241 (0.888–1.735) | 0.207 |