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Table 2 Univariate and multivariate analysis of prognostic variables for patients with resected NSCLC (n = 627)

From: Resectable left lower lobe non–small cell lung cancer with lymph node metastasis is related to unfavorable outcomes

Characteristic

Univariate analysis

Multivariate analysis

HR (95% CI)

P a

HR (95% CI)

P a

Sex (men vs. women)

0.827 (0.633–1.080)

0.162

Age (≤60 years vs. >60 years)

1.076 (0.844–1.371)

0.556

Tumor location

 (Left vs. right lobe)

0.904 (0.705–1.160)

0.428

 (Upper vs. lower lobe)

1.362 (1.068–1.735)

0.013

 (Non-LLL vs. LLL)

1.493 (1.115–1.998)

0.007

1.465 (1.090–1.969)

0.011

T category (T1 vs. T2 vs. T3)

1.492 (1.173–1.898)

0.001

N category (N0 vs. N1–2)

2.749 (2.152–3.512)

0.000

2.742 (2.145–3.507)

<0.001

Pathology (AC vs. SCC vs. others)

1.103 (0.927–1.312)

0.269

Histology grade (G1 vs. G2 vs. G3)

1.267 (1.071–1.499)

0.006

Tumor size (≤4 vs. >4 cm)

1.617 (1.266–2.065)

0.000

1.474 (1.151–1.888)

0.002

Pleural invasion (no vs. yes)

1.627 (1.099–2.408)

0.015

Resection (lobectomy vs. bilobectomy)

1.555 (1.013–2.386)

0.044

Adjuvant chemotherapy (yes vs. no)

0.828 (0.644–1.065)

0.141

  1. LLL left lower lobe, non-LLL other lobes, AC adenocarcinoma, SCC squamous cell carcinoma, HR hazard ratio, CI confidence interval
  2. aCox proportional hazards regression analysis (forward stepwise)