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Table 2 Univariate and multivariate analysis of prognostic variables for patients with resected NSCLC (n = 627)

From: Resectable left lower lobe non–small cell lung cancer with lymph node metastasis is related to unfavorable outcomes

Characteristic Univariate analysis Multivariate analysis
HR (95% CI) P a HR (95% CI) P a
Sex (men vs. women) 0.827 (0.633–1.080) 0.162
Age (≤60 years vs. >60 years) 1.076 (0.844–1.371) 0.556
Tumor location
 (Left vs. right lobe) 0.904 (0.705–1.160) 0.428
 (Upper vs. lower lobe) 1.362 (1.068–1.735) 0.013
 (Non-LLL vs. LLL) 1.493 (1.115–1.998) 0.007 1.465 (1.090–1.969) 0.011
T category (T1 vs. T2 vs. T3) 1.492 (1.173–1.898) 0.001
N category (N0 vs. N1–2) 2.749 (2.152–3.512) 0.000 2.742 (2.145–3.507) <0.001
Pathology (AC vs. SCC vs. others) 1.103 (0.927–1.312) 0.269
Histology grade (G1 vs. G2 vs. G3) 1.267 (1.071–1.499) 0.006
Tumor size (≤4 vs. >4 cm) 1.617 (1.266–2.065) 0.000 1.474 (1.151–1.888) 0.002
Pleural invasion (no vs. yes) 1.627 (1.099–2.408) 0.015
Resection (lobectomy vs. bilobectomy) 1.555 (1.013–2.386) 0.044
Adjuvant chemotherapy (yes vs. no) 0.828 (0.644–1.065) 0.141
  1. LLL left lower lobe, non-LLL other lobes, AC adenocarcinoma, SCC squamous cell carcinoma, HR hazard ratio, CI confidence interval
  2. aCox proportional hazards regression analysis (forward stepwise)