SHMT1 C1420T polymorphism contributes to the risk of non-Hodgkin lymphoma: evidence from 7309 patients

Cancer Communications

Table 3 False-positive report probability values and statistical power for associations between genotypes of SHMT1 C1420T polymorphism and NHL risk

Genotype	Positive OR (95% CI)^a	P value^b	Statistical power^c	Prior probability
Genotype	Positive OR (95% CI)^a	P value^b	Statistical power^c	0.25	0.10	0.01	0.001	0.0001
SHMT1 C1420T
T vs. C	1.09 (1.01–1.17)	0.025	1.000	0.070	0.184	0.712	0.962	0.996
TT vs. CC	1.18 (1.00–1.39)	0.046	0.999	0.121	0.293	0.820	0.979	0.998
CT+TT vs. CC	1.10 (1.00–1.21)	0.054	0.820	0.165	0.372	0.867	0.985	0.999

Abbreviations as in Tables 1 and 2
^aThe OR reported in Table 2
^bGenotype frequency distributions were calculated using the omnibus Chi-square test in Table 2
^cStatistical power was calculated using the number of observations (cases and controls) and the OR and P values in Table 2

ISSN: 2523-3548