|
Variable
|
Median OS (months)
|
Univariate analysis
|
Multivariate analysis
|
|---|
|
HR (95% CI)
|
P value
|
HR (95% CI)
|
P value
|
|---|
|
Age
|
|
≥55 years vs. <55 years
|
67.8 vs. 72.2
|
1.08 (0.93–1.25)
|
0.32
|
–
|
–
|
|
Gender
|
|
Males vs. females
|
66.5 vs. 76.6
|
1.17 (1.01–1.37)
|
0.04
|
1.03 (0.82–1.28)
|
0.82
|
|
ECOG PS score
|
|
1 vs. 0
| |
0.97 (0.90–1.04)
|
0.36
|
–
|
–
|
|
Smoking status
|
|
Ever vs. never
|
64.1 vs. 75.8
|
1.19 (1.03–1.37)
|
0.02
|
1.22 (1.06–1.40)
|
0.01
|
|
Pathology
|
|
Squamous vs. non-squamous
|
71.4 vs. 69.1
|
1.00 (0.87–1.16)
|
0.98
|
–
|
–
|
|
pT category
|
|
3/4 vs. 1/2
|
31.0 vs. 79.1
|
2.06 (1.76–2.41)
|
<0.01
|
1.61 (1.35–1.91)
|
<0.01
|
|
pN category
|
|
≥N1 vs. N0
|
39.5 vs. NA
|
2.89 (2.51–3.33)
|
<0.01
|
2.42 (1.95–3.00)
|
<0.01
|
|
pTNM stage
|
|
III vs. I–II
|
34.6 vs. NA
|
2.83 (2.46–3.25)
|
<0.01
|
1.44 (1.16–1.76)
|
0.01
|
|
Surgery type
|
|
Pneumonectomy vs. others
|
28.2 vs. 72.5
|
1.80 (1.41–2.30)
|
<0.01
|
1.24 (0.96–1.60)
|
0.11
|
|
Chemotherapy
|
|
No vs. yes
|
57.9 vs. 83.8
|
1.36 (1.19–1.57)
|
<0.01
|
1.31 (1.12–1.53)
|
<0.01
|
|
Blood type
|
|
Group 2 vs. group 1
|
61.5 vs. 74.9
|
1.20 (1.04–1.38)
|
0.01
|
1.37 (1.10–1.70)
|
<0.01
|
-
CI confidence interval, HR hazard ratio, NA not available. Other abbreviations as in Table 1
