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Table 2 Univariate and multivariate analyses for overall survival (OS) of NSCLC patients
| Variable | Median OS (months) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | ||
| Age | |||||
| ≥55 years vs. <55 years | 67.8 vs. 72.2 | 1.08 (0.93–1.25) | 0.32 | – | – |
| Gender | |||||
| Males vs. females | 66.5 vs. 76.6 | 1.17 (1.01–1.37) | 0.04 | 1.03 (0.82–1.28) | 0.82 |
| ECOG PS score | |||||
| 1 vs. 0 | 0.97 (0.90–1.04) | 0.36 | – | – | |
| Smoking status | |||||
| Ever vs. never | 64.1 vs. 75.8 | 1.19 (1.03–1.37) | 0.02 | 1.22 (1.06–1.40) | 0.01 |
| Pathology | |||||
| Squamous vs. non-squamous | 71.4 vs. 69.1 | 1.00 (0.87–1.16) | 0.98 | – | – |
| pT category | |||||
| 3/4 vs. 1/2 | 31.0 vs. 79.1 | 2.06 (1.76–2.41) | <0.01 | 1.61 (1.35–1.91) | <0.01 |
| pN category | |||||
| ≥N1 vs. N0 | 39.5 vs. NA | 2.89 (2.51–3.33) | <0.01 | 2.42 (1.95–3.00) | <0.01 |
| pTNM stage | |||||
| III vs. I–II | 34.6 vs. NA | 2.83 (2.46–3.25) | <0.01 | 1.44 (1.16–1.76) | 0.01 |
| Surgery type | |||||
| Pneumonectomy vs. others | 28.2 vs. 72.5 | 1.80 (1.41–2.30) | <0.01 | 1.24 (0.96–1.60) | 0.11 |
| Chemotherapy | |||||
| No vs. yes | 57.9 vs. 83.8 | 1.36 (1.19–1.57) | <0.01 | 1.31 (1.12–1.53) | <0.01 |
| Blood type | |||||
| Group 2 vs. group 1 | 61.5 vs. 74.9 | 1.20 (1.04–1.38) | 0.01 | 1.37 (1.10–1.70) | <0.01 |
