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Table 1 Associations between T lymphoma invasion and metastasis 1 (Tiam1) expression and clinicopathologic characteristics of the 194 patients with head and neck squamous cell carcinoma (HNSCC)

From: The prognostic value of Tiam1 protein expression in head and neck squamous cell carcinoma: a retrospective study

Characteristic Tiam1 expression (cases)a P value
Low High
Total 82 112  
Age (years)
 ≤50 29 46 0.836
 51–60 27 34
 61–70 19 25
 >70 7 7
Gender
 Male 59 91 0.127
 Female 23 21
Tobacco use
 No 38 38 0.080
 Yes 44 74
Alcohol use
 No 62 85 0.964
 Yes 20 27
Histological differentiation
 Well 48 67 0.289
 Moderate 28 30  
 Poor 6 15  
Chronic illness
 No 66 90 0.982
 Yes 16 22
T stage
 T1/T2 73 90 0.104
 T3/T4 9 22
Lymph node metastasis
 No 65 66 0.003
 Yes 17 46
Clinical stage
 I/II 62 57 <0.001
 III/IV 20 55
Tumor position
 Oral cavity 71 85 0.064
 Buccal mucosa 7 6
 Floor of mouth 3 8
 Anterior tongue 51 56
 Alveolar ridge 10 15
 Glottic larynx 8 19
 Supraglottic larynx 3 8
Disease recurrence
 No 45 33 <0.001
 Yes 37 79
  1. aTiam1 expression is scored from 0 to 12. Scores from 0 to 4 indicate low expression; scores of 5 or greater indicate high expression. See the text for details