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Table 2 The relationship between clinical characteristics and overall survival in 224 patients: Cox’s regression analysis

From: Impact of oral anti–hepatitis B therapy on the survival of patients with hepatocellular carcinoma initially treated with chemoembolization

Variable Univariate analysis   Multivariate analysis  
P value   Hazard ratio 95% CI P value  
Age 0.013   0.988 0.975–1.002 0.084  
Sex 0.020   2.424 1.139–5.156 0.022  
HBV DNA (log 10 IU/mL) 0.602   
ALT 0.607   
TNM stage (early:advanced) <0.001   2.031 1.410–2.925 <0.001  
Cycles of TACE 0.346   
AST <0.001   1.001 0.998–1.005 0.496  
ALB 0.043   0.950 0.913–0.988 0.010  
TBIL 0.028   1.007 0.986–1.029 0.511  
AFP <0.001   1.400 0.979–2.003 0.066  
APTT 0.259   
Antiviral treatment 0.044   0.635 0.454–0.888 0.008  
Local ablation <0.001   0.241 0.133–0.436 <0.001  
Resection <0.001   0.298 0.148–0.599 0.001  
HBeAg 0.977   
PT 0.746   
Sorafenib therapy 0.825   
Chemotherapeutic agents (epirubicin only:>2 agents) 0.798   
  1. CI, confidence interval. Other abbreviations as in Table 1.