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Table 2 The relationship between clinical characteristics and overall survival in 224 patients: Cox’s regression analysis

From: Impact of oral anti–hepatitis B therapy on the survival of patients with hepatocellular carcinoma initially treated with chemoembolization

Variable

Univariate analysis

 

Multivariate analysis

 

P value

 

Hazard ratio

95% CI

P value

 

Age

0.013

 

0.988

0.975–1.002

0.084

 

Sex

0.020

 

2.424

1.139–5.156

0.022

 

HBV DNA (log 10 IU/mL)

0.602

 

 

ALT

0.607

 

 

TNM stage (early:advanced)

<0.001

 

2.031

1.410–2.925

<0.001

 

Cycles of TACE

0.346

 

 

AST

<0.001

 

1.001

0.998–1.005

0.496

 

ALB

0.043

 

0.950

0.913–0.988

0.010

 

TBIL

0.028

 

1.007

0.986–1.029

0.511

 

AFP

<0.001

 

1.400

0.979–2.003

0.066

 

APTT

0.259

 

 

Antiviral treatment

0.044

 

0.635

0.454–0.888

0.008

 

Local ablation

<0.001

 

0.241

0.133–0.436

<0.001

 

Resection

<0.001

 

0.298

0.148–0.599

0.001

 

HBeAg

0.977

 

 

PT

0.746

 

 

Sorafenib therapy

0.825

 

 

Chemotherapeutic agents (epirubicin only:>2 agents)

0.798

 

 
  1. CI, confidence interval. Other abbreviations as in Table 1.