%PDF-1.6
%
1 0 obj
<>
endobj
2 0 obj
<>stream
2018-04-30T18:41:08+05:30
Springer
2018-05-04T20:22:28+02:00
2018-05-04T20:22:28+02:00
Acrobat Distiller 10.1.8 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version)
Acquired drug resistance,Homogenization,Intratumor heterogeneity,Plasticity,Precision medicine
application/pdf
https://doi.org/10.1186/s40880-018-0287-y
BioMed Central
Cancer Communications, https://doi.org/10.1186/s40880-018-0287-y
Acquired drug resistance
Homogenization
Intratumor heterogeneity
Plasticity
Precision medicine
New insights from the widening homogeneity perspective to target intratumor heterogeneity
Mengying Tong
Ziqian Deng
Xiaolong Zhang
Bin He
Mengying Yang
Wei Cheng
Quentin Liu
10.1186/s40880-018-0287-y
2010-04-23
true
springer.com
springerlink.com
https://doi.org/10.1186/s40880-018-0287-y
10.1186/s40880-018-0287-y
2523-3548
journal
Cancer Communications
The Author(s)
2010-04-23
true
10.1186/s40880-018-0287-y
noindex
springer.com
springerlink.com
VoR
uuid:9388f2c4-788c-4624-ae45-8696e5ba2131
uuid:a3c277a8-e96c-4adb-b3e7-316b2f54dd49
default
1
converted
uuid:809c7fac-276b-4b4e-b6a9-95bc3b753aa8
converted to PDF/A-2b
pdfToolbox
2018-04-30T18:41:51+05:30
2
B
http://ns.adobe.com/pdfx/1.3/
pdfx
Adobe Document Info PDF eXtension Schema
external
Mirrors crossmark:MajorVersionDate
CrossmarkMajorVersionDate
Text
external
Mirrors crossmark:CrossmarkDomainExclusive
CrossmarkDomainExclusive
Text
internal
Mirrors crossmark:DOI
doi
Text
external
Mirrors crossmark:CrosMarkDomains
CrossMarkDomains
seq Text
internal
A name object indicating whether the document has been modified to include trapping information
robots
Text
internal
ID of PDF/X standard
GTS_PDFXVersion
Text
internal
Conformance level of PDF/X standard
GTS_PDFXConformance
Text
internal
Company creating the PDF
Company
Text
internal
Date when document was last modified
SourceModified
Text
http://crossref.org/crossmark/1.0/
crossmark
Crossmark Schema
internal
Usual same as prism:doi
DOI
Text
external
The date when a publication was publishe.
MajorVersionDate
Text
internal
CrossmarkDomainExclusive
CrossmarkDomainExclusive
Text
internal
CrossMarkDomains
CrossMarkDomains
seq Text
http://prismstandard.org/namespaces/basic/2.0/
prism
Prism Schema
external
This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary.
url
URI
external
The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL).
doi
Text
external
ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version.
issn
Text
internal
Volume number
volume
Text
internal
Issue number
number
Text
internal
Starting page
startingPage
Text
internal
Ending page
endingPage
Text
external
The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary.
aggregationType
Text
external
Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.”
publicationName
Text
external
Copyright
copyright
Text
http://ns.adobe.com/pdf/1.3/
pdf
Adobe PDF Schema
internal
A name object indicating whether the document has been modified to include trapping information
Trapped
Text
http://ns.adobe.com/xap/1.0/mm/
xmpMM
XMP Media Management Schema
internal
UUID based identifier for specific incarnation of a document
InstanceID
URI
internal
The common identifier for all versions and renditions of a document.
DocumentID
URI
internal
The common identifier for all versions and renditions of a document.
OriginalDocumentID
URI
http://www.aiim.org/pdfa/ns/id/
pdfaid
PDF/A ID Schema
internal
Part of PDF/A standard
part
Integer
internal
Amendment of PDF/A standard
amd
Text
internal
Conformance level of PDF/A standard
conformance
Text
http://www.niso.org/schemas/jav/1.0/
jav
NISO
external
Values for Journal Article Version are one of the following:
AO = Author’s Original
SMUR = Submitted Manuscript Under Review
AM = Accepted Manuscript
P = Proof
VoR = Version of Record
CVoR = Corrected Version of Record
EVoR = Enhanced Version of Record
journal_article_version
Closed Choice of Text
endstream
endobj
3 0 obj
<>
endobj
8 0 obj
[9 0 R 10 0 R 11 0 R 12 0 R 13 0 R 14 0 R 15 0 R 16 0 R 17 0 R 18 0 R 19 0 R 20 0 R 21 0 R 22 0 R 23 0 R 24 0 R 25 0 R 26 0 R 27 0 R 28 0 R 29 0 R 30 0 R 31 0 R 32 0 R 33 0 R 34 0 R 35 0 R 36 0 R 37 0 R 38 0 R 39 0 R 40 0 R 41 0 R 42 0 R]
endobj
9 0 obj
<>/Rect[94.6349 619.868 104.474 607.702]/H/N/AP<>>>
endobj
10 0 obj
<>/Rect[110.527 619.868 120.366 607.702]/H/N/AP<>>>
endobj
11 0 obj
<>/Rect[255.468 571.868 265.307 559.702]/H/N/AP<>>>
endobj
12 0 obj
<>/Rect[179.69 511.868 189.53 499.702]/H/N/AP<>>>
endobj
13 0 obj
<>/Rect[275.283 427.868 285.122 415.702]/H/N/AP<>>>
endobj
14 0 obj
<>/Rect[59.8876 391.868 69.7268 379.702]/H/N/AP<>>>
endobj
15 0 obj
<>/Rect[143.217 391.868 153.057 379.702]/H/N/AP<>>>
endobj
16 0 obj
<>/Rect[186.166 355.868 196.005 343.702]/H/N/AP<>>>
endobj
17 0 obj
<>/Rect[200.937 355.868 210.776 343.702]/H/N/AP<>>>
endobj
18 0 obj
<>/Rect[182.344 331.868 192.184 319.702]/H/N/AP<>>>
endobj
19 0 obj
<>/Rect[198.112 331.868 207.952 319.702]/H/N/AP<>>>
endobj
20 0 obj
<>/Rect[59.8876 319.868 69.7268 307.702]/H/N/AP<>>>
endobj
21 0 obj
<>/Rect[75.7839 319.868 85.6231 307.702]/H/N/AP<>>>
endobj
22 0 obj
<>/Rect[217.514 223.868 222.434 211.702]/H/N/AP<>>>
endobj
23 0 obj
<>/Rect[275.283 199.868 285.122 187.702]/H/N/AP<>>>
endobj
24 0 obj
<>/Rect[230.64 175.868 240.48 163.702]/H/N/AP<>>>
endobj
25 0 obj
<>/Rect[275.283 175.868 285.122 163.702]/H/N/AP<>>>
endobj
26 0 obj
<>/Rect[86.5856 163.868 96.4248 151.702]/H/N/AP<>>>
endobj
27 0 obj
<>/Rect[187.847 163.868 197.686 151.702]/H/N/AP<>>>
endobj
28 0 obj
<>/Rect[126.707 115.868 136.546 103.702]/H/N/AP<>>>
endobj
29 0 obj
<>/Rect[231.854 79.8684 241.693 67.7018]/H/N/AP<>>>
endobj
30 0 obj
<>/Rect[247.622 79.8684 257.461 67.7018]/H/N/AP<>>>
endobj
31 0 obj
<>/Rect[390.452 430.634 400.291 418.467]/H/N/AP<>>>
endobj
32 0 obj
<>/Rect[459.403 430.634 469.243 418.467]/H/N/AP<>>>
endobj
33 0 obj
<>/Rect[370.088 418.634 379.927 406.467]/H/N/AP<>>>
endobj
34 0 obj
<>/Rect[386.12 418.634 395.959 406.467]/H/N/AP<>>>
endobj
35 0 obj
<>/Rect[507.761 358.634 517.6 346.467]/H/N/AP<>>>
endobj
36 0 obj
<>/Rect[407.934 346.634 417.774 334.467]/H/N/AP<>>>
endobj
37 0 obj
<>/Rect[526.509 238.634 536.348 226.467]/H/N/AP<>>>
endobj
38 0 obj
<>/Rect[304.724 226.634 314.564 214.467]/H/N/AP<>>>
endobj
39 0 obj
<>/Rect[460.315 202.634 470.154 190.467]/H/N/AP<>>>
endobj
40 0 obj
<>/Rect[505.682 178.634 515.521 166.467]/H/N/AP<>>>
endobj
41 0 obj
<>/Rect[330.639 142.634 340.478 130.467]/H/N/AP<>>>
endobj
42 0 obj
<>/Rect[475.721 130.634 485.56 118.467]/H/N/AP<>>>
endobj
6 0 obj
<>/XObject<>/ProcSet[/PDF/Text/ImageC]/Font<>/Properties<>>>
endobj
5 0 obj
<>stream
x\YFrX?aX`4֎44#`wqãTŚVϵGf2y!tw+E/oWVϿO_Hqi{0("$J(mw)JH_n}c/Kvt]w|N?+jWƞt<͜ws5;VϮ]{_uMl}1%N@
I)@R/(IiNRǦۋmك8^-]G^