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  1. Content type: Original article

    Oxaliplatin, irinotecan, 5-fluorouracil, and l-leucovorin (FOLFIRINOX) has become one of the first-line treatment options for advanced pancreatic cancer (PC). However, the relatively high rate of grade 3 or 4 adv...

    Authors: Zhi-Qiang Wang, Fei Zhang, Ting Deng, Le Zhang, Fen Feng, Feng-Hua Wang, Wei Wang, De-Shen Wang, Hui-Yan Luo, Rui-Hua Xu, Yi Ba and Yu-Hong Li

    Citation: Cancer Communications 2019 39:26

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  2. Content type: Original article

    In the post-Z0011 trial era, the need to perform surgical axillary staging for early-stage breast cancer patients, who are treated with breast-conserving therapy (BCT), is being questioned. We conducted a retr...

    Authors: Jin Wang, Hailin Tang, Xing Li, Cailu Song, Zhenchong Xiong, Xi Wang, Xiaoming Xie and Jun Tang

    Citation: Cancer Communications 2019 39:25

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  3. Content type: Original article

    Tumor hypoxia is associated with metastasis and resistance to chemotherapy and radiotherapy. Genes involved in oxygen-sensing are clinically relevant and have significant implications for prognosis. In this st...

    Authors: Wai Hoong Chang, Donall Forde and Alvina G. Lai

    Citation: Cancer Communications 2019 39:23

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  4. Content type: Original article

    Radical cystectomy and urinary diversion remains the standard surgical treatment for patients with muscle-invasive or high-risk or recurrent non-muscle-invasive bladder cancer. Although this approach prolongs ...

    Authors: Zhiyong Li, Zhuowei Liu, Kai Yao, Zike Qin, Hui Han, Yonghong Li, Pei Dong, Yunlin Ye, Yanjun Wang, Zhiming Wu, Zhiling Zhang and Fangjian Zhou

    Citation: Cancer Communications 2019 39:19

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  5. Content type: Original article

    Internal tandem duplications (ITD) within the juxtamembrane domain of FMS-like tyrosine kinase 3 (FLT3) represent a poor prognostic indicator in acute myeloid leukemia (AML). Therapeutic benefits of tyrosine k...

    Authors: Xin You, Weiye Jiang, Wenhua Lu, Hui Zhang, Tiantian Yu, Jingyu Tian, Shijun Wen, Guillermo Garcia-Manero, Peng Huang and Yumin Hu

    Citation: Cancer Communications 2019 39:17

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  6. Content type: Original article

    The benefit of systemic treatments in esophageal squamous cell carcinoma (ESCC) which has progressed after chemotherapy is still uncertain and optimal regimens based on randomized trials have not yet been esta...

    Authors: Jing Huang, Binghe Xu, Ying Liu, Junxing Huang, Ping Lu, Yi Ba, Lin Wu, Yuxian Bai, Shu Zhang, Jifeng Feng, Ying Cheng, Jie Li, Lu Wen, Xianglin Yuan, Changwu Ma, Chunhong Hu…

    Citation: Cancer Communications 2019 39:16

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  7. Content type: Original article

    Currently, the diagnosis and treatment of nasopharyngeal carcinoma (NPC) patients with residual cervical lymphadenopathy following radical radiotherapy with or without chemotherapy are challenging. We investig...

    Authors: Sai-Lan Liu, Xue-Song Sun, Xiao-Yun Li, Lin-Quan Tang, Qiu-Yan Chen, Huan-Xin Lin, Yu-Jing Liang, Jin-Jie Yan, Chao Lin, Shan-Shan Guo, Li-Ting Liu, Yang Li, Hao-Jun Xie, Qing-Nan Tang, Hu Liang, Ling Guo…

    Citation: Cancer Communications 2019 39:14

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  8. Content type: Review

    Robust and clinically convenient biomarkers for cancer diagnosis, early detection, and prognosis have great potential to improve patient survival and are the key to precision medicine. The advent of next-gener...

    Authors: Chang Zeng, Emily Kunce Stroup, Zhou Zhang, Brian C.-H. Chiu and Wei Zhang

    Citation: Cancer Communications 2019 39:12

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  9. Content type: Guideline and Consensus

    China is one of the countries with the highest incidence of gastric cancer. There are differences in epidemiological characteristics, clinicopathological features, tumor biological characteristics, treatment p...

    Authors: Feng-Hua Wang, Lin Shen, Jin Li, Zhi-Wei Zhou, Han Liang, Xiao-Tian Zhang, Lei Tang, Yan Xin, Jing Jin, Yu-Jing Zhang, Xiang-Lin Yuan, Tian-Shu Liu, Guo-Xin Li, Qi Wu, Hui-Mian Xu, Jia-Fu Ji…

    Citation: Cancer Communications 2019 39:10

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  10. Content type: Original article

    Identification of activated epidermal growth factor receptor (EGFR) mutations and application of EGFR-tyrosine kinase inhibitors (EGFR-TKIs) have greatly changed the therapeutic strategies of non-small-cell lung ...

    Authors: Fang Wang, Xia-Yao Diao, Xiao Zhang, Qiong Shao, Yan-Fen Feng, Xin An and Hai-Yun Wang

    Citation: Cancer Communications 2019 39:7

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  11. Content type: Correction

    In the original publication of this article [1], the number of death cases in ‘Materials and methods’ section is incorrect.

    Authors: Jie Liu, Xu-li Yang, Si-Wei Zhang, Li-Ping Zhu and Wan-Qing Chen

    Citation: Cancer Communications 2019 39:6

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    The original article was published in Cancer Communications 2018 38:75

  12. Content type: Study Protocol

    Glioblastoma (GBM) is a highly virulent tumor of the central nervous system, with a median survival < 15 months. Clearly, an improvement in treatment outcomes is needed. However, the emergence of these maligna...

    Authors: Lin Kong, Jing Gao, Jiyi Hu, Rong Lu, Jing Yang, Xianxin Qiu, Weixu Hu and Jiade J. Lu

    Citation: Cancer Communications 2019 39:5

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  13. Content type: Original article

    Little is known about the correlation between the clinicopathological features, postoperative treatment, and prognosis of multiple gastric cancers (MGCs). In this study, we aimed to investigate the correlation...

    Authors: Jian-Xian Lin, Zu-Kai Wang, Jian-Wei Xie, Jia-Bin Wang, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, Ze-Ning Huang, Ju-Li Lin, Chao-Hui Zheng, Chang-Ming Huang and Ping Li

    Citation: Cancer Communications 2019 39:4

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  14. Content type: Original article

    In our previous study, we identified a candidate tumor suppressor gene, testin LIM domain protein (TES), in primary gastric cancer (GC). TES contains three LIM domains, which are specific interacting regions for ...

    Authors: Dan-dan Wang, Yi-bing Chen, Jing-jing Zhao, Xiao-fei Zhang, Guang-chao Zhu, De-sheng Weng, Ke Pan, Lin Lv, Qiu-zhong Pan, Shan-shan Jiang, Lei-lei Wang and Jian-chuan Xia

    Citation: Cancer Communications 2019 39:3

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  15. Content type: Original article

    Epithelial–mesenchymal transition (EMT) is implicated in the metastatic process and presents a challenge to epithelial cell adhesion molecule-based detection of circulating tumor cells (CTCs), which have been ...

    Authors: Xiuwen Guan, Fei Ma, Chunxiao Li, Shiyang Wu, Shangying Hu, Jiefen Huang, Xiaoying Sun, Jiayu Wang, Yang Luo, Ruigang Cai, Ying Fan, Qiao Li, Shanshan Chen, Pin Zhang, Qing Li and Binghe Xu

    Citation: Cancer Communications 2019 39:1

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  16. Content type: Original article

    Thus far, the incidence, mortality, and temporal trend data of oropharyngeal cancers (OPC) in China were few. We estimated the incidence, mortality, and temporal patterns of OPC in China during 2008–2012 accor...

    Authors: Jie Liu, Xu-li Yang, Si-Wei Zhang, Li-Ping Zhu and Wan-Qing Chen

    Citation: Cancer Communications 2018 38:75

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    The Correction to this article has been published in Cancer Communications 2019 39:6

  17. Content type: Original article

    Postradiation nasopharyngeal necrosis (PRNN) is a severe complication after radiotherapy in patients with nasopharyngeal carcinoma (NPC), which can severely affect the quality of life and threaten the patient’...

    Authors: Xiong Zou, Shun-Lan Wang, You-Ping Liu, Yan-Ling Liu, Ru-Hai Zou, Yi-Nuan Zhang, Rui You, Qi Yang, Yu-Long Xie, Mei Lin, Pei-Yu Huang, Rou Jiang, Meng-Xia Zhang, Chao-Nan Qian, Hai-Qiang Mai, Ling Guo…

    Citation: Cancer Communications 2018 38:74

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  18. Content type: Original article

    The preliminary results of our phase II randomized trial reported comparable functional sphincter preservation rates and short-term survival outcomes between patients undergoing total mesorectal excision (TME)...

    Authors: Fulong Wang, Wenhua Fan, Jianhong Peng, Zhenhai Lu, Zhizhong Pan, Liren Li, Yuanhong Gao, Hui Li, Gong Chen, Xiaojun Wu, Peirong Ding, Zhifan Zeng and Desen Wan

    Citation: Cancer Communications 2018 38:73

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  19. Content type: Original article

    An increasing number of cancer patients die of cardiovascular diseases. The cardiotoxicity of chemotherapy is particularly important in triple-negative breast cancer (TNBC) with limited therapeutic options. Ca...

    Authors: Binliang Liu, Tao An, Meiying Li, Zongbi Yi, Chunxiao Li, Xiaoying Sun, Xiuwen Guan, Lixi Li, Yanfeng Wang, Yuhui Zhang, Binghe Xu, Fei Ma and Yixin Zeng

    Citation: Cancer Communications 2018 38:71

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  20. Content type: Original article

    Desmoplastic small round cell tumor (DSRCT) is a rare, aggressive, and poorly investigated simple sarcoma with a low frequency of genetic deregulation other than an Ewing sarcoma RNA binding protein 1 (EWSR1)-Wil...

    Authors: Andrea Devecchi, Loris De Cecco, Matteo Dugo, Donata Penso, Gianpaolo Dagrada, Silvia Brich, Silvia Stacchiotti, Marialuisa Sensi, Silvana Canevari and Silvana Pilotti

    Citation: Cancer Communications 2018 38:70

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  21. Content type: Original article

    The 8th American Joint Committee on Cancer tumor–node–metastasis (AJCC-TNM) staging system is based on a few retrospective single-center studies. We aimed to test the prognostic validity of the staging system ...

    Authors: Zai-Shang Li, Antonio Augusto Ornellas, Christian Schwentner, Xiang Li, Alcides Chaux, Georges Netto, Arthur L. Burnett, Yong Tang, JiunHung Geng, Kai Yao, Xiao-Feng Chen, Bin Wang, Hong Liao, Nan Liu, Peng Chen, Yong-Hong Lei…

    Citation: Cancer Communications 2018 38:68

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  22. Content type: Original article

    The 8th edition of the American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) pathological tumor-node-metastasis (pTNM) staging system may have increased accuracy in predicting p...

    Authors: Cheng Fang, Wei Wang, Jing-Yu Deng, Zhe Sun, Sharvesh Raj Seeruttun, Zhen-Ning Wang, Hui-Mian Xu, Han Liang and Zhi-Wei Zhou

    Citation: Cancer Communications 2018 38:67

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  23. Content type: Original article

    Famitinib is a tyrosine kinase inhibitor against multiple targets, including vascular endothelial growth factor receptor 2/3, platelet-derived growth factor receptor, and stem cell factor receptor (c-kit). Pre...

    Authors: Qiuyan Chen, Linquan Tang, Na Liu, Feng Han, Ling Guo, Shanshan Guo, Jianwei Wang, Huai Liu, Yanfang Ye, Lu Zhang, Liting Liu, Pan Wang, Yingqin Li, Qingmei He, Xiaoqun Yang, Qingnan Tang…

    Citation: Cancer Communications 2018 38:66

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  24. Content type: Editorial

    Cancer cells uniquely reprogram their cellular activities to support their rapid proliferation and migration and to counteract metabolic and genotoxic stress during cancer progression. In this reprograming, ca...

    Authors: Yugang Wang, Yan Xia and Zhimin Lu

    Citation: Cancer Communications 2018 38:65

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  25. Content type: Original article

    Recent studies highlight pseudogene derived long non-coding RNAs (lncRNAs) as key regulators of cancer biology. However, few of them have been well characterized in pancreatic cancer. Here, we aimed to identif...

    Authors: Yifan Lian, Jiebin Yang, Yikai Lian, Chuangxing Xiao, Xuezhen Hu and Hongzhi Xu

    Citation: Cancer Communications 2018 38:64

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  26. Content type: Original article

    Natural killer/T-cell lymphoma (NKTCL) is a highly aggressive non-Hodgkin lymphoma often resistant to chemotherapy. Serum level of soluble IL-2 receptor α (IL-2Rα) is elevated in NKTCL patients and correlates ...

    Authors: Liang Wang, Xi-wen Bi, Yu-jia Zhu, Ying-zhi He, Qiu-yu Lai, Zhong-jun Xia and Qing-qing Cai

    Citation: Cancer Communications 2018 38:62

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  27. Content type: Original article

    The optimal strategy for adjuvant therapy after curative resection for hepatocellular carcinoma (HCC) patients with solitary tumor and microvascular invasion (MVI) is controversial. This trial evaluated the ef...

    Authors: Wei Wei, Pei-En Jian, Shao-Hua Li, Zhi-Xing Guo, Yong-Fa Zhang, Yi-Hong Ling, Xiao-Jun Lin, Li Xu, Ming Shi, Lie Zheng, Min-Shan Chen and Rong-Ping Guo

    Citation: Cancer Communications 2018 38:61

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  28. Content type: Original article

    Patient-derived organoids and xenografts (PDXs) have emerged as powerful models in functional diagnostics with high predictive power for anticancer drug response. However, limitations such as engraftment failu...

    Authors: Feifei Zhang, Wenjie Wang, Yuan Long, Hui Liu, Jijun Cheng, Lin Guo, Rongyu Li, Chao Meng, Shan Yu, Qingchuan Zhao, Shun Lu, Lili Wang, Haitao Wang and Danyi Wen

    Citation: Cancer Communications 2018 38:60

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  29. Content type: Original article

    Due to the occult anatomic location of the nasopharynx and frequent presence of adenoid hyperplasia, the positive rate for malignancy identification during biopsy is low, thus leading to delayed or missed diag...

    Authors: Chaofeng Li, Bingzhong Jing, Liangru Ke, Bin Li, Weixiong Xia, Caisheng He, Chaonan Qian, Chong Zhao, Haiqiang Mai, Mingyuan Chen, Kajia Cao, Haoyuan Mo, Ling Guo, Qiuyan Chen, Linquan Tang, Wenze Qiu…

    Citation: Cancer Communications 2018 38:59

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  30. Content type: Original article

    Breast cancer stem cells (BCSCs) are considered responsible for cancer relapse and drug resistance. Understanding the identity of BCSCs may open new avenues in breast cancer therapy. Although several discoveri...

    Authors: Mengying Tong, Ziqian Deng, Mengying Yang, Chang Xu, Xiaolong Zhang, Qingzheng Zhang, Yuwei Liao, Xiaodi Deng, Dekang Lv, Xuehong Zhang, Yu Zhang, Peiying Li, Luyao Song, Bicheng Wang, Aisha Al-Dherasi, Zhiguang Li…

    Citation: Cancer Communications 2018 38:56

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  31. Content type: Original article

    The tumor–node–metastasis (TNM) staging system does not perform well for guiding individualized induction or adjuvant chemotherapy for patients with locoregionally advanced nasopharyngeal carcinoma (NPC). We a...

    Authors: Pu-Yun OuYang, Kai-Yun You, Lu-Ning Zhang, Yao Xiao, Xiao-Min Zhang and Fang-Yun Xie

    Citation: Cancer Communications 2018 38:55

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  32. Content type: Original article

    Treatment guidelines for a variety of cancers have been increasingly used in clinical practice, and have resulted in major improvement in patient outcomes. However, recommended regimens (even first-line treatm...

    Authors: Peng Zhao, Hui Chen, Danyi Wen, Shuo Mou, Feifei Zhang and Shusen Zheng

    Citation: Cancer Communications 2018 38:54

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  33. Content type: Original article

    We previously found that overexpression of the gene known as amplified in breast cancer 1 (AIB1) was associated with lymph node metastasis and poor prognosis in patients with lung adenocarcinoma. However, the rol...

    Authors: Liru He, Haixia Deng, Shiliang Liu, Jiewei Chen, Binkui Li, Chenyuan Wang, Xin Wang, Yiguo Jiang, Ningfang Ma, Mengzhong Liu and Dan Xie

    Citation: Cancer Communications 2018 38:53

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