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  1. Multidrug resistance (MDR) occurs frequently after long-term chemotherapy, resulting in refractory cancer and tumor recurrence. Therefore, combatting MDR is an important issue. Autophagy, a self-degradative sy...

    Authors: Ying-Jie Li, Yu-He Lei, Nan Yao, Chen-Ran Wang, Nan Hu, Wen-Cai Ye, Dong-Mei Zhang and Zhe-Sheng Chen

    Citation: Chinese Journal of Cancer 2017 36:52

    Content type: Review

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  2. Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are a heterogeneous group of rare tumors. Many issues in terms of epidemiologic features, pathogenesis, and treatment of GEP-NENs are still under disc...

    Authors: Cheng Fang, Wei Wang, Yu Zhang, Xingyu Feng, Jian Sun, Yujie Zeng, Ye Chen, Yong Li, Minhu Chen, Zhiwei Zhou and Jie Chen

    Citation: Chinese Journal of Cancer 2017 36:51

    Content type: Original article

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  3. Flavonoids are polyphenols that are found in numerous edible plant species. Data obtained from preclinical and clinical studies suggest that specific flavonoids are chemo-preventive and cytotoxic against vario...

    Authors: Haneen Amawi, Charles R. Ashby Jr. and Amit K. Tiwari

    Citation: Chinese Journal of Cancer 2017 36:50

    Content type: Review

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    The Erratum to this article has been published in Chinese Journal of Cancer 2017 36:70

  4. Recent comprehensive investigations clarified that immune microenvironment surrounding tumor cells are deeply involved in tumor progression, metastasis, and response to treatment. Furthermore, several immunoth...

    Authors: Yusuke Takahashi, Noriyuki Matsutani, Takashi Nakayama, Hitoshi Dejima, Hirofumi Uehara and Masafumi Kawamura

    Citation: Chinese Journal of Cancer 2017 36:49

    Content type: Review

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  5. Hypoalbuminemia adversely affects the clinical outcomes of various cancers. The purpose of this study was to estimate the prognostic value of hypoalbuminemia 3–5 weeks after treatment in patients with metastat...

    Authors: Wen Cai, Jin Zhang, Yonghui Chen, Wen Kong, Yiran Huang, Jiwei Huang and Lixin Zhou

    Citation: Chinese Journal of Cancer 2017 36:47

    Content type: Original article

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  6. Thymoma is an uncommon tumor without a widely accepted standard care to date. We aimed to investigate the clinicopathologic variables of patients with thymoma and identify possible predictors of survival and r...

    Authors: Zu-Yang Yuan, Shu-Geng Gao, Ju-Wei Mu, Qi Xue, You-Sheng Mao, Da-Li Wang, Jun Zhao, Yu-Shun Gao, Jin-Feng Huang and Jie He

    Citation: Chinese Journal of Cancer 2017 36:46

    Content type: Original article

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  7. Mature T-cell and natural killer (NK)-cell lymphomas compose a heterogeneous group of non-Hodgkin lymphomas, and extranodal NK/T-cell lymphoma, nasal type (ENKTL) is an aggressive subtype with sporadic CD30 ex...

    Authors: Yanfen Feng, Huilan Rao, Yiyan Lei, Yuhua Huang, Fang Wang, Yu Zhang, Shaoyan Xi, Qiuliang Wu and Jianyong Shao

    Citation: Chinese Journal of Cancer 2017 36:43

    Content type: Original article

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  8. The increasing prevalence of colorectal cancer (CRC) in China and the paucity of information about relevant expenditure highlight the necessity of better understanding the financial burden and effect of CRC di...

    Authors: Hui-Yao Huang, Ju-Fang Shi, Lan-Wei Guo, Ya-Na Bai, Xian-Zhen Liao, Guo-Xiang Liu, A-Yan Mao, Jian-Song Ren, Xiao-Jie Sun, Xin-Yu Zhu, Le Wang, Bing-Bing Song, Ling-Bin Du, Lin Zhu, Ji-Yong Gong, Qi Zhou…

    Citation: Chinese Journal of Cancer 2017 36:41

    Content type: Original article

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  9. Metastasis is the major cause of treatment failure in cancer patients and of cancer-related deaths. This editorial discusses how cancer metastasis may be better perceived and controlled. Based on big-data anal...

    Authors: Chao-Nan Qian, Yan Mei and Jian Zhang

    Citation: Chinese Journal of Cancer 2017 36:38

    Content type: Editorial

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  10. The chemoresistance of prostate cancer (PCa) is invariably associated with the aggressiveness and metastasis of this disease. New emerging evidence indicates that the epithelial-to-mesenchymal transition (EMT)...

    Authors: Wenchu Wang, Lihui Wang, Atsushi Mizokami, Junlin Shi, Chunlin Zou, Jinlu Dai, Evan T. Keller, Yi Lu and Jian Zhang

    Citation: Chinese Journal of Cancer 2017 36:35

    Content type: Original article

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  11. Multifocal pontine glioblastoma exhibiting an exophytic growth pattern in the cerebello-pontine angle (CPA) is rare. We present a case of a 5-year-old girl with consecutive neurological imaging and other clini...

    Authors: Fanfan Chen, Zongyang Li, Chengyin Weng, Peng Li, Lanbo Tu, Lei Chen, Wei Xie and Ling Li

    Citation: Chinese Journal of Cancer 2017 36:34

    Content type: Case report

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  12. Nasopharyngeal carcinoma (NPC) shows a high proportion of lymph node metastasis, and treatment guidelines have been developed for positive nodes. However, no irradiation guidelines have been proposed for patie...

    Authors: Hao Peng, Lei Chen, Rui Guo, Yuan Zhang, Wen-Fei Li, Yan-Ping Mao, Ying Sun, Fan Zhang, Li-Zhi Liu, Li Tian and Jun Ma

    Citation: Chinese Journal of Cancer 2017 36:32

    Content type: Original article

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  13. Laparoscopic hepatectomy for hepatocellular carcinoma (HCC) located in segment VI, VII, or VIII of the liver is usually difficult because of poor operative exposure, due to the unique anatomical structure. In ...

    Authors: Jian-Cong Chen, Rong-Xin Zhang, Min-Shan Chen, Li Xu, Jin-Bin Chen, Ke-Li Yang, Yao-Jun Zhang and Zhong-Guo Zhou

    Citation: Chinese Journal of Cancer 2017 36:31

    Content type: Original article

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  14. Prostate cancer tissue is composed of both cancer cells and host cells. The milieu of host components that compose the tumor is termed the tumor microenvironment (TME). Host cells can be those derived from the...

    Authors: Jinlu Dai, Yi Lu, Hernan Roca, Jill M. Keller, Jian Zhang, Laurie K. McCauley and Evan T. Keller

    Citation: Chinese Journal of Cancer 2017 36:29

    Content type: Review

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  15. Extensive studies have confirmed the efficacy of taxanes in combination with anthracycline-based chemotherapy on breast cancer. However, few studies have assessed the efficacy of weekly taxane–anthracycline re...

    Authors: Qiu-Wen Tan, Ting Luo, Hong Zheng, Ting-Lun Tian, Ping He, Jie Chen, He-Lin Zeng and Qing Lv

    Citation: Chinese Journal of Cancer 2017 36:27

    Content type: Original article

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  16. In the era of intensity-modulated radiotherapy (IMRT), the role of neoadjuvant chemotherapy (NACT) in treating ascending-type nasopharyngeal carcinoma (NPC) is under-evaluated. This study was to compare the ef...

    Authors: Ji-Jin Yao, Xiao-Li Yu, Fan Zhang, Wang-Jian Zhang, Guan-Qun Zhou, Ling-Long Tang, Yan-Ping Mao, Lei Chen, Jun Ma and Ying Sun

    Citation: Chinese Journal of Cancer 2017 36:26

    Content type: Original article

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  17. Cervical cancer is the sixth most common cancer in Chinese women. A standard treatment modality for cervical cancer is the combination of surgery, chemotherapy, external-beam radiotherapy and intracavitary bra...

    Authors: Shen Qian, Ling Ye, Yun-Hong Tian, Li-Gen Wang, Zuo-Ping Huang, Feng Li, Bing Hou, Ni Song, Juan Chen, Ying Liu, Xiao Liu and Tao Zhou

    Citation: Chinese Journal of Cancer 2017 36:24

    Content type: Original article

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  18. Few studies of breast cancer surgery outcomes have used longitudinal data for more than 2 years. This study aimed to validate the use of the artificial neural network (ANN) model to predict the 5-year mortalit...

    Authors: Su-Hsin Huang, Joon-Khim Loh, Jinn-Tsong Tsai, Ming-Feng Houg and Hon-Yi Shi

    Citation: Chinese Journal of Cancer 2017 36:23

    Content type: Original article

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  19. Alcohol consumption and some other dietary habits are thought to be associated with lung cancer incidence. However, the effects of these habits on lung cancer prognosis have been studied rarely. The purpose of...

    Authors: Wentao Li, Lap Ah Tse, Joseph S. K. Au, Kai Shing Yu, Feng Wang and Ignatius Tak-sun Yu

    Citation: Chinese Journal of Cancer 2017 36:21

    Content type: Original article

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  20. The proportion of never-smokers with non-small cell lung cancer (NSCLC) is increasing, but that in Korea has not been well addressed in a large population. We aimed to evaluate the proportion and clinical feat...

    Authors: Jaeyoung Cho, Sun Mi Choi, Jinwoo Lee, Chang-Hoon Lee, Sang-Min Lee, Dong-Wan Kim, Jae-Joon Yim, Young Tae Kim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han and Young Sik Park

    Citation: Chinese Journal of Cancer 2017 36:20

    Content type: Original article

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  21. Hepatocellular carcinoma (HCC) is a common malignant tumor in the world, especially in China. As a member of the inhibitor of differentiation (Id) family, Id4 has been reported to function in many cancer types, b...

    Authors: Yang Zhang, Li-Xing Zhang, Xiao-Qin Liu, Fang-Yu Zhao, Chao Ge, Tao-Yang Chen, Ming Yao and Jin-Jun Li

    Citation: Chinese Journal of Cancer 2017 36:19

    Content type: Original article

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  22. Obesity is recognized as the second highest risk factor for cancer. The pathogenic mechanisms underlying tobacco-related cancers are well characterized and effective programs have led to a decline in smoking a...

    Authors: Ajit Venniyoor

    Citation: Chinese Journal of Cancer 2017 36:18

    Content type: Editorial

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  23. Metformin, an inexpensive and well-tolerated oral agent commonly used in the first-line treatment of type 2 diabetes, has become the focus of intense research as a candidate anticancer agent. Here, we discuss ...

    Authors: Yong Lei, Yanhua Yi, Yang Liu, Xia Liu, Evan T. Keller, Chao-Nan Qian, Jian Zhang and Yi Lu

    Citation: Chinese Journal of Cancer 2017 36:17

    Content type: Review

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  24. Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer-related death, and new prognostic biomarkers are urgently needed. Apoptosis-stimulating P53-binding protein 1 (ASPP1) and 2 (ASPP2) have b...

    Authors: Xiao-Feng Xie, Qing Yang, Jun Chi, Xian-Zi Yang, Hui-Yun Wang and Guo-Liang Xu

    Citation: Chinese Journal of Cancer 2017 36:15

    Content type: Original article

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  25. Percutaneous radiofrequency ablation (RFA) is a first-line treatment for very-early-stage hepatocellular carcinoma (HCC), whereas the efficacy of percutaneous microwave ablation (MWA) for very-early-stage HCC ...

    Authors: Yun Xu, Qiang Shen, Neng Wang, Pan-Pan Wu, Bin Huang, Ming Kuang and Guo-Jun Qian

    Citation: Chinese Journal of Cancer 2017 36:14

    Content type: Original article

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  26. Chemotherapy toxicity is a serious problem from which non-small cell lung cancer (NSCLC) patients suffer. The mismatch repair (MMR) system is associated with platinum-based chemotherapy toxicity in NSCLC patie...

    Authors: Jun-Yan Liu, Chen-Yue Qian, Yuan-Feng Gao, Juan Chen, Hong-Hao Zhou and Ji-Ye Yin

    Citation: Chinese Journal of Cancer 2017 36:12

    Content type: Original article

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  27. Ankyrin repeat and SOCS box protein 3 (ASB3) is a member of ASB family and contains ankyrin repeat sequence and SOCS box domain. Previous studies indicated that it mediates the ubiquitination and degradation o...

    Authors: Wu-Ying Du, Zhen-Hai Lu, Wen Ye, Xiang Fu, Yi Zhou, Chun-Mei Kuang, Jiang-Xue Wu, Zhi-Zhong Pan, Shuai Chen, Ran-Yi Liu and Wen-Lin Huang

    Citation: Chinese Journal of Cancer 2017 36:11

    Content type: Original article

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  28. Metastatic melanoma has long been considered to have a very poor prognosis and to be chemo-resistant. However, a subgroup of patients with metastatic melanoma presents remarkable responses to chemotherapeutic ...

    Authors: Aurélien Simon, Hampig Raphael Kourie and Joseph Kerger

    Citation: Chinese Journal of Cancer 2017 36:10

    Content type: Case report

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  29. The optimal treatment strategy for biliary tract cancer (BTC) after curative-intent resection remains controversial. The purpose of this study was to evaluate the efficacy of fluoropyrimidine-based adjuvant ch...

    Authors: Young Saing Kim, Chi-Young Jeong, Haa-Na Song, Tae Hyo Kim, Hong Jun Kim, Young-Joon Lee and Soon Chan Hong

    Citation: Chinese Journal of Cancer 2017 36:9

    Content type: Original article

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  30. Concurrent chemoradiotherapy (CCRT) significantly increases the survival rate of esophageal squamous cell carcinoma (ESCC) patients with malignant fistulae. Recent clinical evidence has shown the benefits of e...

    Authors: Li Ma, Guang-Yu Luo, Yu-Feng Ren, Bo Qiu, Hong Yang, Chun-Xia Xie, Song-Ran Liu, Shi-Liang Liu, Zhao-Lin Chen, Qun Li, Jian-Hua Fu, Meng-Zhong Liu, Yong-Hong Hu, Wen-Feng Ye and Hui Liu

    Citation: Chinese Journal of Cancer 2017 36:8

    Content type: Original article

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  31. Body mass index (BMI) has a U-shaped association with lung cancer risk. However, the effect of BMI on prognosis is controversial. This retrospective study aimed to investigate the effect of BMI on the survival...

    Authors: Hao-Jun Xie, Xu Zhang, Zhen-Qiang Wei, Hao Long, Tie-Hua Rong and Xiao-Dong Su

    Citation: Chinese Journal of Cancer 2017 36:7

    Content type: Original article

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  32. Chemotherapy-induced nausea and vomiting adversely affects the quality of life of patients who receive chemotherapy via intravenous infusion or transcatheter arterial chemoembolization (TACE). This study aimed...

    Authors: Jing Xie, Lei-Hua Chen, Zhou-Yu Ning, Chen-Yue Zhang, Hao Chen, Zhen Chen, Zhi-Qiang Meng and Xiao-Yan Zhu

    Citation: Chinese Journal of Cancer 2017 36:6

    Content type: Original article

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  33. Ras protein signaling pathways are important in controlling the plight of different types of cancer. Here we discussed the paper entitled “Small molecule stabilization of the KSR inactive state antagonizes onc...

    Authors: Syed Lal Badshah and Yahia Mabkhot

    Citation: Chinese Journal of Cancer 2017 36:5

    Content type: Editorial

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  34. Birt–Hogg–Dubé (BHD) syndrome, a hereditary renal cancer syndrome caused by mutations in the folliculin (FLCN) gene, is characterized by the presence of fibrofolliculomas, pulmonary cysts, spontaneous pneumothora...

    Authors: Teng Li, Xianghui Ning, Qun He and Kan Gong

    Citation: Chinese Journal of Cancer 2017 36:4

    Content type: Case report

    Published on:

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