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  1. Autophagy plays a crucial role in chemotherapy resistance of triple-negative breast cancer (TNBC). Hence, autophagy-related gene 5 (ATG5), an essential molecule involved in autophagy regulation, is presumably ...

    Authors: Meiying Li, Fei Ma, Jiayu Wang, Qing Li, Pin Zhang, Peng Yuan, Yang Luo, Ruigang Cai, Ying Fan, Shanshan Chen, Qiao Li and Binghe Xu

    Citation: Chinese Journal of Cancer 2018 37:4

    Content type: Original article

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  2. Accurate evaluation of lymph node metastasis in bladder cancer (BCa) is important for disease staging, treatment selection, and prognosis prediction. In this study, we aimed to evaluate the diagnostic accuracy...

    Authors: Yong Li, Feiyu Diao, Siya Shi, Kaiwen Li, Wangshu Zhu, Shaoxu Wu and Tianxin Lin

    Citation: Chinese Journal of Cancer 2018 37:3

    Content type: Original Article

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  3. We previously showed that the expression of follistatin-like protein 1 (FSTL1) was significantly down-regulated in metastatic clear-cell renal cell carcinoma (ccRCC). In this study, we aimed to characterize th...

    Authors: Yan Liu, Xiaojie Tan, Wenbin Liu, Xi Chen, Xiaomei Hou, Dan Shen, Yibo Ding, Jianhua Yin, Ling Wang, Hongwei Zhang, Yongwei Yu, Jianguo Hou, Timothy C. Thompson and Guangwen Cao

    Citation: Chinese Journal of Cancer 2018 37:2

    Content type: Original article

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  4. According to the 7th edition of the American Joint Committee on Cancer (AJCC) staging system, over 50% of patients with nasopharyngeal carcinoma (NPC) have N1 disease at initial diagnosis. However, patients wi...

    Authors: Ji-Jin Yao, Guan-Qun Zhou, Ya-Qin Wang, Si-Yang Wang, Wang-Jian Zhang, Ya-Nan Jin, Fan Zhang, Li Li, Li-Zhi Liu, Zhi-Bin Cheng, Jun Ma, Zhen-Yu Qi and Ying Sun

    Citation: Chinese Journal of Cancer 2017 36:98

    Content type: Original article

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  5. Metastatic colorectal cancer (mCRC) patients with progressive disease after all available standard therapies need new medication for further treatment. Famitinib is a small-molecule multikinase inhibitor, with...

    Authors: Rui-Hua Xu, Lin Shen, Ke-Ming Wang, Gang Wu, Chun-Mei Shi, Ke-Feng Ding, Li-Zhu Lin, Jin-Wan Wang, Jian-Ping Xiong, Chang-Ping Wu, Jin Li, Yun-Peng Liu, Dong Wang, Yi Ba, Jue-Ping Feng, Yu-Xian Bai…

    Citation: Chinese Journal of Cancer 2017 36:97

    Content type: Original Article

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  6. The prognostic nutritional index (PNI) has been widely applied for predicting survival outcomes of patients with various malignant tumors. Although a low PNI predicts poor prognosis in patients with colorectal...

    Authors: Jianhong Peng, Rongxin Zhang, Yixin Zhao, Xiaojun Wu, Gong Chen, Desen Wan, Zhenhai Lu and Zhizhong Pan

    Citation: Chinese Journal of Cancer 2017 36:96

    Content type: Original article

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  7. Little is known about the nature of metastasis to small cervical lymph nodes (SCLNs) in the patients with nasopharyngeal carcinoma (NPC) examined by using 18-fluoro-2-deoxy-glucose (18F-FDG) positron emission tom...

    Authors: Hao Peng, Lei Chen, Ling-Long Tang, Wen-Fei Li, Yan-Ping Mao, Rui Guo, Yuan Zhang, Li-Zhi Liu, Li Tian, Xu Zhang, Xiao-Ping Lin, Ying Guo, Ying Sun and Jun Ma

    Citation: Chinese Journal of Cancer 2017 36:95

    Content type: Original article

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  8. The programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) pathway inhibits the activation of T cells and plays a crucial role in the negative regulation of cellular and humoral immune responses...

    Authors: Li-Yang Hu, Xiao-Lu Xu, Hui-Lan Rao, Jie Chen, Ren-Chun Lai, Hui-Qiang Huang, Wen-Qi Jiang, Tong-Yu Lin, Zhong-Jun Xia and Qing-Qing Cai

    Citation: Chinese Journal of Cancer 2017 36:94

    Content type: Original Article

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  9. Locoregional recurrence remains the challenge for long-term survival of non-small cell lung cancer (NSCLC) patients after radical surgery, and curative-intent radiotherapy could be a treatment choice. This stu...

    Authors: Li Ma, Bo Qiu, Jun Zhang, Qi-Wen Li, Bin Wang, Xu-Hui Zhang, Meng-Yun Qiang, Zhao-Lin Chen, Su-Ping Guo and Hui Liu

    Citation: Chinese Journal of Cancer 2017 36:93

    Content type: Original article

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  10. The Szent-Györgyi Prize for Progress in Cancer Research is a prestigious scientific award sponsored by the National Foundation for Cancer Research (NFCR)—a leading cancer research charitable organization in th...

    Authors: Hali Hartmann, Jie Zhao and Sujuan Ba

    Citation: Chinese Journal of Cancer 2017 36:92

    Content type: Editorial

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  11. We estimated the incidence and mortality of nasopharyngeal carcinoma (NPC) in China in 2010 according to the data of 145 domestic population-based cancer registries in 2014, and no such reports since then. Hen...

    Authors: Kuang-Rong Wei, Rong-Shou Zheng, Si-Wei Zhang, Zhi-Heng Liang, Zhu-Ming Li and Wan-Qing Chen

    Citation: Chinese Journal of Cancer 2017 36:90

    Content type: Original article

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  12. Voltage-gated sodium channel 1.5 (Nav1.5) potentially promotes the migratory and invasive behaviors of colon cancer cells. Hitherto, the prognostic significance of Nav1.5 expression remains undetermined. The p...

    Authors: Jianhong Peng, Qingjian Ou, Xiaojun Wu, Rongxin Zhang, Qian Zhao, Wu Jiang, Zhenhai Lu, Desen Wan, Zhizhong Pan and Yujing Fang

    Citation: Chinese Journal of Cancer 2017 36:89

    Content type: Original article

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  13. Glutamine and glutamate are known to play important roles in cancer biology. However, no detailed information is available in terms of their levels of involvement in various biological processes across differe...

    Authors: Yuan Tian, Wei Du, Sha Cao, Yue Wu, Ning Dong, Yan Wang and Ying Xu

    Citation: Chinese Journal of Cancer 2017 36:88

    Content type: Original article

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  14. The value of Epstein–Barr virus (EBV) DNA assay during posttreatment follow-up of the patients with nasopharyngeal carcinoma (NPC) presenting with different pretreatment plasma EBV DNA levels remains unclear. ...

    Authors: Wen-Fei Li, Yuan Zhang, Xiao-Bin Huang, Xiao-Jing Du, Ling-Long Tang, Lei Chen, Hao Peng, Rui Guo, Ying Sun and Jun Ma

    Citation: Chinese Journal of Cancer 2017 36:87

    Content type: Original article

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  15. Conditional survival (CS) has been established as a clinically relevant prognostic factor for cancer survivors, and the CS in gallbladder (GB) cancer has not yet been fully evaluated. In this study, we evaluat...

    Authors: Yi-Jun Kim and Kyubo Kim

    Citation: Chinese Journal of Cancer 2017 36:85

    Content type: Original article

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  16. Stage at diagnosis and molecular subtype are important clinical factors associated with breast cancer patient survival. However, subgroup survival data from a large study sample are limited in China. To estima...

    Authors: Tingting Zuo, Hongmei Zeng, Huichao Li, Shuo Liu, Lei Yang, Changfa Xia, Rongshou Zheng, Fei Ma, Lifang Liu, Ning Wang, Lixue Xuan and Wanqing Chen

    Citation: Chinese Journal of Cancer 2017 36:84

    Content type: Original article

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  17. Transarterial chemoembolization (TACE) is recommended as the standard care for unresectable hepatocellular carcinoma (HCC) at Barcelona Clinic Liver Cancer (BCLC) stage A–B. However, the efficacy of TACE on la...

    Authors: Min-Ke He, Yong Le, Qi-Jiong Li, Zi-Shan Yu, Shao-Hua Li, Wei Wei, Rong-Ping Guo and Ming Shi

    Citation: Chinese Journal of Cancer 2017 36:83

    Content type: Original article

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  18. The prognostic role of the V600E mutation of v-raf murine sarcoma viral oncogene homolog B1 (BRAF) in metastatic colorectal cancer (mCRC) is well established, but the therapeutic regimen targeting this disease is...

    Authors: Xicheng Wang, Qing Wei, Jing Gao, Jian Li, Jie Li, Jifang Gong, Yanyan Li and Lin Shen

    Citation: Chinese Journal of Cancer 2017 36:81

    Content type: Original article

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  19. Recent studies indicate that C-X-C motif chemokine receptor 4 (CXCR4) and its ligand, C-X-C motif chemokine ligand 12 (CXCL12), stimulate expression of the cell cycle regulatory protein Cyclin D1 in neurofibro...

    Authors: Chao Zhang, Fang-Yuan Chang, Wen-Ya Zhou and Ji-Long Yang

    Citation: Chinese Journal of Cancer 2017 36:80

    Content type: Original article

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  20. Pathologic response is evaluated according to the extent of tumor regression and is used to estimate the efficacy of preoperative treatment. Several studies have reported the association between the pathologic...

    Authors: Yun Wang, Yun-Fei Yuan, Hao-Cheng Lin, Bin-Kui Li, Feng-Hua Wang, Zhi-Qiang Wang, Pei-Rong Ding, Gong Chen, Xiao-Jun Wu, Zhen-Hai Lu, Zhi-Zhong Pan, De-Sen Wan, Peng Sun, Shu-Mei Yan, Rui-Hua Xu and Yu-Hong Li

    Citation: Chinese Journal of Cancer 2017 36:78

    Content type: Original article

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  21. Reduced expression of tripartite motif-containing 3 (TRIM3) has been reported to be involved in the pathogenesis of human glioblastoma. In our previous research, we found that TRIM3 expression was markedly reduce...

    Authors: Xu-Qiong Huang, Xiao-Fei Zhang, Jin-Hua Xia, Jie Chao, Qiu-Zhong Pan, Jing-Jing Zhao, Zi-Qi Zhou, Chang-Long Chen, Yan Tang, De-Sheng Weng, Jian-Hua Zhang and Jian-Chuan Xia

    Citation: Chinese Journal of Cancer 2017 36:77

    Content type: Original article

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  22. To protect neurological tissues, underdosing occurs in most cases of T4 nasopharyngeal carcinoma (NPC) with intracranial extension. In this study, we aimed to evaluate the effect of dosimetric inadequacy on lo...

    Authors: Fen Xue, Chao-Su Hu and Xia-Yun He

    Citation: Chinese Journal of Cancer 2017 36:76

    Content type: Original article

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  23. Inflammation-based indexes have been used to predict survival and recurrence in cancer patients. Systemic immune-inflammation index (SII) was reported to be associated with prognosis in some malignant tumors. ...

    Authors: Kang Wang, Feiyu Diao, Zhijun Ye, Xinhua Zhang, Ertao Zhai, Hui Ren, Tong Li, Hui Wu, Yulong He, Shirong Cai and Jianhui Chen

    Citation: Chinese Journal of Cancer 2017 36:75

    Content type: Original article

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  24. Controlled-release oxycodone/naloxone (OXN-CR) maintains the effect of opioid-induced analgesia through oxycodone while reducing the occurrence rate of opioid-induced constipation through naloxone. The present...

    Authors: Kyung-Hee Lee, Tae Won Kim, Jung-Hun Kang, Jin-Soo Kim, Jin-Seok Ahn, Sun-Young Kim, Hwan-Jung Yun, Young-Jun Eum, Sung Ae Koh, Min Kyoung Kim, Yong Sang Hong, Jeong Eun Kim and Gyeong-Won Lee

    Citation: Chinese Journal of Cancer 2017 36:74

    Content type: Original article

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  25. Esophageal cancer is associated with substantial disease burden in China, and data on the economic burden are fundamental for setting priorities in cancer interventions. The medical expenditure for the diagnos...

    Authors: Lan-Wei Guo, Hui-Yao Huang, Ju-Fang Shi, Li-Hong Lv, Ya-Na Bai, A-Yan Mao, Xian-Zhen Liao, Guo-Xiang Liu, Jian-Song Ren, Xiao-Jie Sun, Xin-Yu Zhu, Jin-Yi Zhou, Ji-Yong Gong, Qi Zhou, Lin Zhu, Yu-Qin Liu…

    Citation: Chinese Journal of Cancer 2017 36:73

    Content type: Original article

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  26. Erythrocytosis, a rare paraneoplastic syndrome, generally occurs in patients with clear cell renal cell carcinoma and has never been reported in patients with chromophobe renal cell carcinoma.

    Authors: Renbo Guo, Yiran Liang, Lei Yan, Zhonghua Xu and Juchao Ren

    Citation: Chinese Journal of Cancer 2017 36:72

    Content type: Case report

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  27. In China, most patients with nasopharyngeal carcinoma (NPC) are diagnosed at a late stage and consequently have a poor prognosis. This study aimed to investigate potential factors associated with the clinical ...

    Authors: Jun-Ting Ren, Meng-Yu Li, Xiao-Wen Wang, Wen-Qiong Xue, Ze-Fang Ren and Wei-Hua Jia

    Citation: Chinese Journal of Cancer 2017 36:71

    Content type: Original article

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  28. Five-year survival rate for patients with all cancers combined, in China, is only 30.9%, which is much lower than those in developed countries. The three main reasons for the low cancer curative rates in China...

    Authors: Chao-Nan Qian

    Citation: Chinese Journal of Cancer 2017 36:68

    Content type: Editorial

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  29. Cancer immunotherapy has finally joined the pillars of cancer treatment—surgery, radiation, chemotherapy, hormonal therapy, and targeted therapy—in improving cancer patient lives. In the last 5 years, the deve...

    Authors: Amit Jain, Qing Zhang and Han-Chong Toh

    Citation: Chinese Journal of Cancer 2017 36:67

    Content type: Editorial

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  30. Population-based cancer registration data are collected by the National Central Cancer Registry in China every year. Cancer incident cases and cancer deaths in 2013 were analyzed.

    Authors: Rongshou Zheng, Hongmei Zeng, Siwei Zhang and Wanqing Chen

    Citation: Chinese Journal of Cancer 2017 36:66

    Content type: Short report

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  31. Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy, with a high incidence and poor prognosis. In the past several decades, hundreds of proteins have been reported to be associated with the p...

    Authors: Chunni Wang, Jingnan Wang, Zhaoli Chen, Yibo Gao and Jie He

    Citation: Chinese Journal of Cancer 2017 36:65

    Content type: Original article

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  32. Sorafenib and sunitinib are widely used as first-line targeted therapy for metastatic renal cell carcinoma (mRCC) in China. This study aimed to compare the efficacy, safety, and quality of life (QoL) in Chines...

    Authors: Wen Cai, Wen Kong, Baijun Dong, Jin Zhang, Yonghui Chen, Wei Xue, Yiran Huang, Lixin Zhou and Jiwei Huang

    Citation: Chinese Journal of Cancer 2017 36:64

    Content type: Original article

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  33. The mitogen-activated extracellular signal-regulated kinase 1/2 (MEK1/2) inhibitor trametinib has shown promising therapeutic effects on melanoma, but its efficacy on colorectal cancer (CRC) is limited. Synthe...

    Authors: Rong Geng, Xin Tan, Zhixiang Zuo, Jiangxue Wu, Zhizhong Pan, Wei Shi, Ranyi Liu, Chen Yao, Gaoyuan Wang, Jiaxin Lin, Lin Qiu, Wenlin Huang and Shuai Chen

    Citation: Chinese Journal of Cancer 2017 36:63

    Content type: Original article

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  34. The prognostic significance of ABO blood type for lymphoma is largely unknown. We evaluated the prognostic role of ABO blood type in patients with extranodal natural killer (NK)/T-cell lymphoma (ENKTL).

    Authors: Ya-Jun Li, Ping-Yong Yi, Ji-Wei Li, Xian-Ling Liu, Tian Tang, Pei-Ying Zhang and Wen-Qi Jiang

    Citation: Chinese Journal of Cancer 2017 36:62

    Content type: Original article

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  35. Anti-programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) immunotherapy has been proved to be effective on gastric cancer in ongoing clinical trials. However, the value of PD-L1 in predicting responses of...

    Authors: Yuan Gao, Su Li, Dazhi Xu, Shangxiang Chen, Yuchen Cai, Wenqi Jiang, Xinke Zhang, Jin Sun, Kefeng Wang, Boyang Chang, Fenghua Wang and Minghuang Hong

    Citation: Chinese Journal of Cancer 2017 36:61

    Content type: Original article

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  36. Patients with intermediate to advanced hepatocellular carcinoma (HCC) are most commonly treated with transarterial chemoembolization (TACE). Previous studies showed that TACE combined with recombinant human ad...

    Authors: Chao-Bin He, Xiang-Ming Lao and Xiao-Jun Lin

    Citation: Chinese Journal of Cancer 2017 36:59

    Content type: Original article

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  37. Mortality outcomes in trials of low-dose computed tomography (CT) screening for lung cancer are inconsistent. This study aimed to evaluate whether CT screening in urban areas of China could reduce lung cancer ...

    Authors: Zixing Wang, Wei Han, Weiwei Zhang, Fang Xue, Yuyan Wang, Yaoda Hu, Lei Wang, Chunwu Zhou, Yao Huang, Shijun Zhao, Wei Song, Xin Sui, Ruihong Shi and Jingmei Jiang

    Citation: Chinese Journal of Cancer 2017 36:57

    Content type: Original article

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  38. Right upper lobectomy (RUL) for lung cancer with different dissecting orders involves the most variable anatomical structures, but no studies have analyzed its effects on postoperative recovery. This study com...

    Authors: Hao-Ran Zhai, Xue-Ning Yang, Qiang Nie, Ri-Qiang Liao, Song Dong, Wei Li, Ben-Yuan Jiang, Jin-Ji Yang, Qing Zhou, Hai-Yan Tu, Xu-Chao Zhang, Yi-Long Wu and Wen-Zhao Zhong

    Citation: Chinese Journal of Cancer 2017 36:53

    Content type: Original article

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