Table 7 Cell cycle alteration after treatment with bortezomib (Bor) and temozolomide (TMZ)
Cell line | Group | Percentage of cells in different cell cycle phases (%) | ||
|---|---|---|---|---|
G1 | S | G2 | ||
U251 | 20 nmol/L Bor | 52.5 ± 3.99 | 35.98 ± 2.96 | 11.52 ± 1.66 |
200 μmol/L TMZ | 54.45 ± 4.88 | 32.77 ± 3.25 | 12.78 ± 1.42 | |
Bor + TMZ | 78.31 ± 5.54 | 13.83 ± 1.58 | 7.86 ± 1.26 | |
U87 | 20 nmol/L Bor | 45.67 ± 2.99 | 30.73 ± 2.53 | 23.63 ± 1.88 |
200 μmol/L TMZ | 66.44 ± 4.33 | 26.19 ± 2.20 | 7.37 ± 1.94 | |
Bor + TMZ | 81.40 ± 6.51 | 12.22 ± 1.54 | 6.42 ± 2.25 | |