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Table 6 Cell apoptosis after treatment with bortezomib (Bor) and temozolomide (TMZ)

From: Bortezomib inhibits growth and sensitizes glioma to temozolomide (TMZ) via down-regulating the FOXM1–Survivin axis

Cell line Group Cell apoptosis rate (%)
Total Early-stage Late-stage
U251 20 nmol/L Bor 11.23 ± 2.22 4.75 ± 0.92 6.48 ± 0.51
200 μmol/L TMZ 11.06 ± 2.63 7.26 ± 1.52 3.80 ± 0.76
Bor + TMZ 40.96 ± 3.88 11.68 ± 0.97 29.28 ± 2.56
U87 20 nmol/L Bor 8.84 ± 1.99 4.06 ± 0.54 4.78 ± 0.88
200 μmol/L TMZ 14.52 ± 1.36 6.68 ± 0.25 7.84 ± 1.92
Bor + TMZ 51.52 ± 3.59 20.33 ± 2.58 31.22 ± 2.18