Table 6 Cell apoptosis after treatment with bortezomib (Bor) and temozolomide (TMZ)
Cell line | Group | Cell apoptosis rate (%) | ||
|---|---|---|---|---|
Total | Early-stage | Late-stage | ||
U251 | 20 nmol/L Bor | 11.23 ± 2.22 | 4.75 ± 0.92 | 6.48 ± 0.51 |
200 μmol/L TMZ | 11.06 ± 2.63 | 7.26 ± 1.52 | 3.80 ± 0.76 | |
Bor + TMZ | 40.96 ± 3.88 | 11.68 ± 0.97 | 29.28 ± 2.56 | |
U87 | 20 nmol/L Bor | 8.84 ± 1.99 | 4.06 ± 0.54 | 4.78 ± 0.88 |
200 μmol/L TMZ | 14.52 ± 1.36 | 6.68 ± 0.25 | 7.84 ± 1.92 | |
Bor + TMZ | 51.52 ± 3.59 | 20.33 ± 2.58 | 31.22 ± 2.18 | |