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Table 5 Combination index of the temozolomide (TMZ) in combination with different concentrations of bortezomib (Bor)

From: Bortezomib inhibits growth and sensitizes glioma to temozolomide (TMZ) via down-regulating the FOXM1–Survivin axis

Bor

U251

U87

Dose (nmol/L)

Effect

Combination index

Effect

Combination index

2

0.24

0.74

0.33

0.67

5

0.32

0.64

0.42

0.61

8

0.38

0.60

0.58

0.44

10

0.47

0.50

0.61

0.44

15

0.71

0.29

0.71

0.38

20

0.85

0.19

0.85

0.23

  1. TMZ was used at a constant dose of 200 μmol/L. Effect: cell viability inhibition rate
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Cancer Communications

ISSN: 2523-3548

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