Skip to main content

Table 5 Combination index of the temozolomide (TMZ) in combination with different concentrations of bortezomib (Bor)

From: Bortezomib inhibits growth and sensitizes glioma to temozolomide (TMZ) via down-regulating the FOXM1–Survivin axis

Bor U251 U87
Dose (nmol/L) Effect Combination index Effect Combination index
2 0.24 0.74 0.33 0.67
5 0.32 0.64 0.42 0.61
8 0.38 0.60 0.58 0.44
10 0.47 0.50 0.61 0.44
15 0.71 0.29 0.71 0.38
20 0.85 0.19 0.85 0.23
  1. TMZ was used at a constant dose of 200 μmol/L. Effect: cell viability inhibition rate