Fig. 2
From: Post-translational modification of Parkin and its research progress in cancer
Function of Parkin. a Proteasome degradation pathway. b Pathway of PINK1 activation of Parkin leading to autophagy of depolarized mitochondria. c Degradation pathway of unfolded or misfolded proteins. ub ubiquitin, OMM outer mitochondrial membrane, P phosphorylation, CCCP carbonyl cyanide 3-chlorophenylhydrazone