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Table 2 Multivariate Cox regression analysis including all variables without surgery type for overall survival of hepatoblastoma patients

From: Incidence trends and survival prediction of hepatoblastoma in children: a population-based study

Characteristic HR 95% CI P value
Sex
 Male Reference   
 Female 0.72 0.44–1.18 0.195
Ethnicity
 Caucasian Reference   
 African–American 2.88 1.55–5.36 0.001
 Others 1.02 0.54–1.94 0.947
Age at diagnosis (years)
 0–1 Reference   
 2–4 1.64 1.03–2.61 0.038
 5–18 1.06 0.41–2.71 0.909
Year of diagnosis
 2004–2007 Reference   
 2008–2011 0.68 0.40–1.16 0.155
 2012–2015 0.84 0.47–1.48 0.540
Tumor size
 ≤ 5 cm Reference   
 > 5 cm 3.81 0.92–15.72 0.065
 Unknown 6.13 1.39–27.09 0.017
Tumor stage
 Local Reference   
 Regional 2.04 1.10–3.79 0.024
 Distant 3.42 1.87–6.26 < 0.001
 Unstaged 2.49 0.77–8.07 0.129
AFP status
 Negative Reference   
 Positive 2.19 0.30–16.15 0.442
 Unknown 3.01 0.39–23.18 0.291
  1. HR hazard ratio, CI confidence interval, AFP alpha-fetoprotein