Table 1 Demographic and clinicopathologic characteristics, and overall survival of patients with hepatoblastoma
From: Incidence trends and survival prediction of hepatoblastoma in children: a population-based study
Characteristic | Patients [cases (%)] | Deaths [cases (%)] | Overall survival rate (%) | P value | |
|---|---|---|---|---|---|
5-year | 10-year | ||||
All patients | 511 | 82 | 81.5 | 81.0 | |
Sex | 0.139 | ||||
Male | 320 (62.6) | 58 (70.7) | 79.3 | 78.4 | |
Female | 191 (37.4) | 24 (29.3) | 85.6 | 85.6 | |
Ethnicity | 0.001 | ||||
Caucasian | 392 (76.7) | 55 (67.1) | 83.9 | 83.9 | |
African–American | 44 (8.6) | 15 (18.3) | 58.4 | 58.4 | |
Others | 75 (14.7) | 12 (14.6) | 82.5 | 79.0 | |
Age at diagnosis | 0.013 | ||||
0–1 | 323 (63.2) | 41 (50.0) | 85.8 | 85.8 | |
2–4 | 152 (29.7) | 36 (43.9) | 72.9 | 71.0 | |
5–18 | 36 (7.1) | 5 (6.1) | 79.9 | 79.9 | |
Year of diagnosis | 0.108 | ||||
2004–2007 | 150 (29.4) | 35 (42.7) | 76.6 | 75.8 | |
2008–2011 | 175 (34.2) | 25 (30.5) | 84.8 | NR | |
2012–2015 | 186 (36.4) | 22 (26.8) | NR | NR | |
Tumor size | < 0.001 | ||||
≤ 5 cm | 60 (11.7) | 2 (2.4) | 96.4 | 96.4 | |
> 5 cm | 400 (78.3) | 62 (75.6) | 82.2 | 81.5 | |
Unknown | 51 (10.0) | 18 (22.0) | 60.4 | 60.4 | |
Tumor stage | < 0.001 | ||||
Local | 231 (45.2) | 17 (20.7) | 91.0 | 91.0 | |
Regional | 157 (30.7) | 27 (32.9) | 80.4 | 80.4 | |
Distant | 109 (21.3) | 34 (41.5) | 65.7 | 65.7 | |
Unstaged | 14 (2.7) | 4 (4.9) | 77.4 | 64.5 | |
AFP status | 0.028 | ||||
Negative | 10 (2.0) | 1 (1.2) | 89.4 | 89.4 | |
Positive | 421 (82.4) | 61 (74.4) | 83.4 | 82.7 | |
Unknown | 80 (15.7) | 20 (24.4) | 70.9 | 70.9 | |
Surgery type | < 0.001 | ||||
No surgery | 86 (16.8) | 46 (56.1) | 43.2 | 39.4 | |
Liver resection | 341 (66.7) | 29 (35.4) | 89.3 | 89.3 | |
Liver transplantation | 84 (16.4) | 7 (8.5) | 90.1 | 90.1 | |