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Table 1 Comparison of baseline characteristics between PDAC patients in the OPD and LPD groups

From: Laparoscopic versus open pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: a propensity score matching analysis

Characteristic

Original cohort

P

Matched cohort

P

OPD group

LPD group

OPD group

LPD group

Total (cases)

230

79

 

93

55

 

Age [years, median (IQR)]

64.0 (57.0–69.3)

64.0 (56.0–70.0)

0.817

64.0 (59.0–70.5)

63.0 (54.0–69.0)

0.337

Gender [cases (%)]

  

0.027

  

0.959

 Male

140 (60.9)

59 (74.7)

 

68 (73.1)

40 (72.7)

 

 Female

90 (39.1)

20 (25.3)

 

25 (26.9)

15 (27.3)

 

BMI [kg/m2, median (IQR)]

22.5 (20.5–24.2)

23.2 (20.7–25.3)

0.100

22.3 (20.3–23.9)

23.0 (20.7–25.2)

0.107

ASA score [cases (%)]

  

0.059

  

0.149

 1

43 (18.7)

6 (7.6)

 

18 (19.4)

5 (9.1)

 

 2

177 (77.0)

68 (86.1)

 

73 (78.5)

47 (85.5)

 

 3

10 (4.3)

5 (6.3)

 

2 (2.2)

3 (5.5)

 

Charlson comorbidity index [cases (%)]

  

0.324

  

0.356

 0

144 (62.6)

44 (55.7)

 

58 (62.4)

31 (56.4)

 

 1

64 (27.8)

29 (36.7)

 

28 (30.1)

22 (40.0)

 

 ≥ 2

22 (9.6)

6 (7.6)

 

7 (7.5)

2 (3.6)

 

Year of operation [cases (%)]

  

0.256

  

0.447

 2013–2015

114 (49.6)

45 (57.0)

 

55 (59.1)

29 (52.7)

 

 2016–2017

116 (50.4)

34 (43.0)

 

38 (40.9)

26 (47.3)

 

Tumor differentiation [cases (%)]

  

0.006

  

0.421

 Well-moderate

82 (35.7)

42 (53.2)

 

41 (44.1)

28 (50.9)

 

 Poor

148 (64.3)

37 (46.8)

 

52 (55.9)

27 (49.1)

 

Nerve invasion [cases (%)]

  

< 0.001

  

0.131

 Yes

203 (88.3)

44 (55.7)

 

73 (78.5)

37 (67.3)

 

 No

27 (11.7)

35 (44.3)

 

20 (21.5)

18 (32.7)

 

T stage [cases (%)]

  

0.001

  

0.835

 1

61 (26.5)

12 (15.2)

 

15 (16.1)

10 (18.2)

 

 2

158 (68.7)

54 (68.4)

 

73 (78.5)

41 (74.5)

 

 3

11 (4.8)

13 (16.5)

 

5 (5.4)

4 (7.3)

 

N stage [cases (%)]

  

0.942

  

0.886

 0

123 (53.5)

44 (55.7)

 

50 (53.8)

32 (58.2)

 

 1

86 (37.4)

28 (35.4)

 

35 (37.6)

19 (34.5)

 

 2

21 (9.1)

7 (8.9)

 

8 (8.6)

4 (7.3)

 

AJCC TNM stage [cases (%)]

  

0.794

  

0.831

 I

117 (50.9)

37 (46.8)

 

46 (49.5)

30 (54.5)

 

 II

92 (40.0)

35 (44.3)

 

39 (41.9)

21 (38.2)

 

 III

21 (9.1)

7 (8.9)

 

8 (8.6)

4 (7.3)

 

Adjuvant treatment [cases (%)]

  

< 0.001

  

0.701

 Yes

162 (70.4)

31 (39.2)

 

47 (50.5)

26 (47.3)

 

 No

68 (29.6)

48 (60.8)

 

46 (49.5)

29 (52.7)

 
  1. PDAC pancreatic ductal adenocarcinoma, OPD open pancreaticoduodenectomy, LPD laparoscopic pancreaticoduodenectomy, IQR interquartile range, BMI body mass index, ASA American Society of Anesthesiologists score, AJCC American Joint Committee on Cancer. The 8th edition of AJCC TNM staging system was used