|
Variable
|
MYCN status [cases (%)]
|
P value*
|
11q23 status [cases (%)]
|
P value*
|
|---|
|
Amplified
|
Normal
|
Deleted
|
Normal
|
|---|
|
Total
|
12
|
89
| |
40
|
61
| |
|
Sex
|
|
Male
|
7 (58.3)
|
50 (56.2)
|
0.536
|
24 (60.0)
|
33 (54.1)
|
0.682
|
|
Female
|
5 (41.7)
|
39 (43.8)
| |
16 (40.0)
|
28 (45.9)
| |
|
Age (months)
|
|
< 18
|
4 (33.3)
|
12 (13.5)
|
0.095
|
2 (5.0)
|
14 (23.0)
|
0.024
|
|
≥ 18
|
8 (66.7)
|
77 (86.5)
| |
38 (95.0)
|
47 (77.0)
| |
|
Primary tumor site
|
|
Abdomen
|
12 (100.0)
|
76 (85.4)
|
0.436
|
33 (82.5)
|
55 (90.2)
|
0.339
|
|
Thorax
|
0 (0)
|
12 (13.5)
| |
6 (15.0)
|
6 (9.8)
| |
|
Neck
|
0 (0)
|
1 (1.1)
| |
1 (2.5)
|
0 (0)
| |
|
LDH (IU/L)
|
|
< 1500
|
1 (8.3)
|
78 (87.6)
|
<0.001
|
32 (80.0)
|
47 (77.0)
|
0.808
|
|
≥ 1500
|
11 (91.7)
|
11 (12.4)
| |
8 (20.0)
|
14 (23.0)
| |
|
NSE (ng/mL)
|
|
< 370
|
1 (8.3)
|
59 (66.3)
|
< 0.001
|
21 (52.5)
|
39 (63.9)
|
0.302
|
|
≥ 370
|
11 (91.7)
|
30 (33.7)
| |
19 (47.5)
|
22 (36.1)
| |
|
Event
|
|
No
|
1 (8.3)
|
48 (53.9)
|
0.004
|
16 (40.0)
|
33 (54.1)
|
0.118
|
|
Yes
|
11 (91.7)
|
41 (46.1)
| |
24 (60.0)
|
28 (45.9)
| |
- MYCN the v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog, LDH lactate dehydrogenase, NSE neuron-specific enolase
- * The χ2 test was used for statistical analysis
