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Fig. 3 | Cancer Communications

Fig. 3

From: Associations of PGK1 promoter hypomethylation and PGK1-mediated PDHK1 phosphorylation with cancer stage and prognosis: a TCGA pan-cancer analysis

Fig. 3

Association between PGK1 promoter hypomethylation and PGK1 mRNA level elevation in multiple cancer types. a All 11 methylation probes have unanimous values in five types of cancer, and these values are higher in normal tissues than in tumor tissues. M value the methylation level, diff difference, T − N, the methylation levels of probes in tumor tissues minus that in normal tissues. b PGK1 promoter methylation is significantly associated with PGK1 mRNA levels in STAD, BLCA, ESCA, LIHC, and BRCA (*P < 0.05, **P < 0.01, independent variable t test). All statistical tests were two-sided. BRCA breast carcinoma, LIHC liver hepatocellular carcinoma, ESCA esophageal carcinoma, BLCA bladder urothelial carcinoma, STAD stomach adenocarcinoma

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