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Table 2 The sFLC concentrations and abnormal ratios of the investigated 186 patients

From: Poor outcomes of immunoglobulin D multiple myeloma patients in the era of novel agents: a single-center experience

Variable

Baseline

After relapse

IgD subtype (n = 13)

Non-IgD subtypes (n = 173)a

P value

IgD subtype (n = 13)

Non-IgD subtypes (n = 96)

P value

sFLC [mg/L; median (range)]

 κ

12.10 (8.54–186.40)

25.80 (1.49–17,780.00)

0.567

15.60 (8.50–1708.00)

56.00 (7.49–4541.00)

0.655

 λ

129.70 (8.46–4303.00)

28.80 (1.33–17,600.00)

0.151

583.86 (10.51–1092.00)

687.00 (1.33–4000.00)

0.412

κ/λ < 0.01 or > 100 [cases (%)]

4 (30.78)

13 (7.51)

0.021

6 (46.15)

7 (7.29)

< 0.001

  1. sFLC serum free light chain, IgD immunoglobulin D
  2. aSerum-free light chains were only available for 173 cases of MM patients at the time of diagnosis