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Table 1 First appearance of clinical events observed during the follow-up period

From: Microscopic tumor foci in axillary lymph nodes may reveal the recurrence dynamics of breast cancer

Events Undetectable metastases
[pN0(i−), n = 328]
Nanometastases
[pN0(i+), n = 24]
Micrometastases
[pN1mi, n = 25]
Local recurrence 20 (17) 3 (3) 5 (4)
Contralateral breast primary 10 (6) 1 (0) 1 (1)
Second primariesa 19 (15) 3 (3) 2 (2)
Death 46 (41) 4 (4) 3 (2)
Metastases 29 (25) 7 (6) 4 (3)
Total events 124 (104) 18 (16) 15 (12)
  1. The numbers in parentheses represent events occurred within the median follow-up time of 8 years
  2. pN, pathologically diagnosed nodal subcategories; pN0(i−), undetectable tumor deposits; pN0(i+), lymph nodes containing isolated tumor cells (nanometastases); pN1mi, lymph nodes containing tumour foci with the largest diameter ranging between 0.2 mm and 2 mm (micrometastases)
  3. aOther tumours, unrelated to “early breast cancer”, which occured after its diagnosis