Fig. 1
From: Is cancer-related death associated with circadian rhythm?
Scatter plot of the number of deaths by time in hours (a) and in minutes of the day (b), showing the temporal pattern of cancer deaths in acute oncology and cancer palliative wards in Hong Kong, 2008–2016. We found no evidence of a unimodal sinusoidal circadian rhythm (periodicity) in the time of cancer deaths according to the parametric sinusoidal circadian test (Z = 2.06, P = 0.127). Restricted cubic splines using three knots were fitted to model the number of deaths in each hour of the day. The resulting spline fit is graphed as a red line