|
Variable
|
Surgical axillary staging
|
Univariate
|
Multivariate
|
|---|
|
HR (95% CI)
|
P
|
HR (95% CI)
|
P
|
|---|
|
Age (years)
|
|
18–49
|
No
|
Ref.
| |
Ref.
| |
|
Yes
|
0.49 (0.27–0.90)
|
0.021
|
0.45 (0.24–0.86)
|
0.015
|
|
50–64
|
No
|
Ref.
| |
Ref.
| |
|
Yes
|
0.79 (0.51–1.22)
|
0.289
|
0.82 (0.53–1.27)
|
0.374
|
|
65–79
|
No
|
Ref.
| |
Ref.
| |
|
Yes
|
0.80 (0.61–1.06)
|
0.116
|
0.78 (0.59–1.02)
|
0.070
|
|
80–
|
No
|
Ref.
| |
Ref.
| |
|
Yes
|
0.67 (0.50–0.91)
|
0.010
|
0.64 (0.47–0.86)
|
0.004
|
|
T stage
|
|
T1mic
|
No
|
Ref.
| |
Ref.
| |
|
Yes
|
1.01 (0.38–2.68)
|
0.989
|
0.94 (0.35–2.53)
|
0.906
|
|
T1a
|
No
|
Ref.
| |
Ref.
| |
|
Yes
|
0.74 (0.42–1.30)
|
0.290
|
0.73 (0.42–1.30)
|
0.288
|
|
T1b
|
No
|
Ref.
| |
Ref.
| |
|
Yes
|
0.74 (0.52–1.05)
|
0.090
|
0.72 (0.51–1.03)
|
0.069
|
|
T1c
|
No
|
Ref.
| |
Ref.
| |
|
Yes
|
0.70 (0.56–0.88)
|
0.002
|
0.67 (0.54–0.84)
|
0.001
|
|
Grade
|
|
I
|
No
|
Ref.
| |
Ref.
| |
|
Yes
|
0.98 (0.66–1.45)
|
0.918
|
0.98 (0.66–1.46)
|
0.933
|
|
II
|
No
|
Ref.
| |
Ref.
| |
|
Yes
|
0.77 (0.59–1.01)
|
0.056
|
0.74 (0.57–0.97)
|
0.029
|
|
III
|
No
|
Ref.
| |
Ref.
| |
|
Yes
|
0.51 (0.36–0.71)
|
< 0.001
|
0.49 (0.35–0.68)
|
< 0.001
|
|
Unknown
|
No
|
Ref.
| |
Ref.
| |
|
Yes
|
0.98 (0.52–1.83)
|
0.936
|
0.92 (0.49–1.72)
|
0.791
|
|
Histological type
|
|
Ductal
|
No
|
Ref.
| |
Ref.
| |
|
Yes
|
0.75 (0.62–0.92)
|
0.005
|
0.72 (0.59–0.88)
|
0.001
|
|
Lobular
|
No
|
Ref.
| |
Ref.
| |
|
Yes
|
0.62 (0.38–0.97)
|
0.045
|
0.63 (0.39–0.99)
|
0.048
|
|
Favorable
|
No
|
Ref.
| |
Ref.
| |
|
Yes
|
0.96 (0.50–1.84)
|
0.896
|
0.91 (0.47–1.75)
|
0.777
|
|
Others
|
No
|
Ref.
| |
Ref.
| |
|
Yes
|
0.28 (0.06–1.38)
|
0.118
|
0.29 (0.06–1.41)
|
0.124
|
- BCSS breast cancer-specific survival, HR hazard ratios, CI confidence intervals
