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Table 3 Stratified analysis of BCSS in the matched cohort

From: Is surgical axillary staging necessary in women with T1 breast cancer who are treated with breast-conserving therapy?

Variable

Surgical axillary staging

Univariate

Multivariate

HR (95% CI)

P

HR (95% CI)

P

Age (years)

 18–49

No

Ref.

 

Ref.

 

Yes

0.49 (0.27–0.90)

0.021

0.45 (0.24–0.86)

0.015

 50–64

No

Ref.

 

Ref.

 

Yes

0.79 (0.51–1.22)

0.289

0.82 (0.53–1.27)

0.374

 65–79

No

Ref.

 

Ref.

 

Yes

0.80 (0.61–1.06)

0.116

0.78 (0.59–1.02)

0.070

 80–

No

Ref.

 

Ref.

 

Yes

0.67 (0.50–0.91)

0.010

0.64 (0.47–0.86)

0.004

T stage

 T1mic

No

Ref.

 

Ref.

 

Yes

1.01 (0.38–2.68)

0.989

0.94 (0.35–2.53)

0.906

 T1a

No

Ref.

 

Ref.

 

Yes

0.74 (0.42–1.30)

0.290

0.73 (0.42–1.30)

0.288

 T1b

No

Ref.

 

Ref.

 

Yes

0.74 (0.52–1.05)

0.090

0.72 (0.51–1.03)

0.069

 T1c

No

Ref.

 

Ref.

 

Yes

0.70 (0.56–0.88)

0.002

0.67 (0.54–0.84)

0.001

Grade

 I

No

Ref.

 

Ref.

 

Yes

0.98 (0.66–1.45)

0.918

0.98 (0.66–1.46)

0.933

 II

No

Ref.

 

Ref.

 

Yes

0.77 (0.59–1.01)

0.056

0.74 (0.57–0.97)

0.029

 III

No

Ref.

 

Ref.

 

Yes

0.51 (0.36–0.71)

< 0.001

0.49 (0.35–0.68)

< 0.001

 Unknown

No

Ref.

 

Ref.

 

Yes

0.98 (0.52–1.83)

0.936

0.92 (0.49–1.72)

0.791

Histological type

 Ductal

No

Ref.

 

Ref.

 

Yes

0.75 (0.62–0.92)

0.005

0.72 (0.59–0.88)

0.001

 Lobular

No

Ref.

 

Ref.

 

Yes

0.62 (0.38–0.97)

0.045

0.63 (0.39–0.99)

0.048

 Favorable

No

Ref.

 

Ref.

 

Yes

0.96 (0.50–1.84)

0.896

0.91 (0.47–1.75)

0.777

 Others

No

Ref.

 

Ref.

 

Yes

0.28 (0.06–1.38)

0.118

0.29 (0.06–1.41)

0.124

  1. BCSS breast cancer-specific survival, HR hazard ratios, CI confidence intervals