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Fig. 4 | Cancer Communications

Fig. 4

From: Dual prognostic role of 2-oxoglutarate-dependent oxygenases in ten cancer types: implications for cell cycle regulation and cell adhesion maintenance

Fig. 4

Relationship between patients’ risks as determined by gene signatures and common genetic mutations. Patients were median-stratified into low or high-risk groups using a signature 1 (green panels) and b signature 2 (red panels). Since signature 1 is a marker of good prognosis, high-risk patients had a lower mean expression of signature 1 genes. Signature 2 is a marker of poor prognosis, hence high-risk patients had a higher mean expression of signature 2 genes. Kaplan–Meier plots depict combined relation of somatic mutations with signatures 1 or 2 on overall survival in cancer patients. P values were calculated from the log-rank test

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