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Table 2 Ingenuity analysis of top ranked pathways of differentially involved metabolites between BaF3/ITD and BaF3/ITD-R cells

From: Metabolic reprogramming and redox adaptation in sorafenib-resistant leukemia cells: detected by untargeted metabolomics and stable isotope tracing analysis

Pathway Ratioa P value
Purine ribonucleoside degradation to ribose-1 phosphate 6/12 (50%) 1.93E−08
Purine nucleotides degradation 6/17 (35.3%) 2.43E−07
Adenine and adenosine salvage 4/10 (40.0%) 1.85E−05
Adenosine nucleotides degradation 4/11 (36.4%) 2.87E−05
Guanosine nucleotides degradation 3/10 (30.0%) 6.35E−04
  1. aRatio: The number of molecules from the focus gene set that map to the pathway to the total number of molecules that map to the canonical pathway