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Fig. 2 | Cancer Communications

Fig. 2

From: Disrupting redox stabilizer: a novel therapeutic strategy for colorectal cancer

Fig. 2

Disrupting the redox homeostasis by inhibition of NADPH-producing enzyme such as MTHFD2 as a novel therapeutic strategy for colorectal cancer. Abbreviations: NADPH, nicotinamide adenine dinucleotide phosphate; NADP+, triphosphopyridine nucleotide; G-6-PD, glucose-6-phosphate dehydrogenase; MTHFD 2, methylenetetrahydrofolate dehydrogenase 2; GSH, reduced glutathione; GSSG, oxidized glutathione; ROS, reactive oxygen species

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