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Table 3 Relationships between ECG abnormalities and chemotherapeutic drugs

From: The association between early-onset cardiac events caused by neoadjuvant or adjuvant chemotherapy in triple-negative breast cancer patients and some novel autophagy-related polymorphisms in their genomic DNA: a real-world study

Drug Total (cases) ST-T segment abnormalities Elevated myocardial enzymes Arrhythmia QRS pattern or duration abnormalities
No. of events [cases (%)] χ2 P value No. of events [cases (%)] χ2 P value No. of events [cases (%)] χ2 P value No. of events [cases (%)] χ2 P value
Anthracyclines 89 32 (36.0) 3.031 0.082 3 (3.4) 0.007 0.935 30 (33.7) 0.274 0.601 12 (13.5) 4.104 0.043
Cyclophosphamide 81 27 (33.3) 0.629 0.428 2 (2.5) 0.000 1.000 28 (34.6) 0.051 0.821 10 (12.3) 1.667 0.197
Paclitaxel 62 18 (29.0) 0.126 0.723 2 (3.2) 0.000 1.000 20 (32.3) 0.455 0.500 6 (9.7) 0.003 0.957
Docetaxel 59 13 (22.0) 3.414 0.065 2 (3.4) 0.000 1.000 25 (42.4) 2.112 0.146 4 (6.8) 0.411 0.521
Carboplatin 43 8 (18.6) 4.126 0.042 2 (2.3) 0.135 0.713 16 (37.2) 0.090 0.765 2 (4.6) 0.971 0.324