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Fig. 6 | Cancer Communications

Fig. 6

From: The genomics of desmoplastic small round cell tumor reveals the deregulation of genes related to DNA damage response, epithelial–mesenchymal transition, and immune response

Fig. 6

Chromosome 1 gains in DSRCTs. a Plot representing genomic location of amplified segments of chromosome 1 in the six DSRCT cases. Recurrent gains were identified in four cases (DSRCT2, 3, 5, and 7). The cases are classified into three groups (see coloured vertical bars on the left). b Network showing genes mapping to chromosome 1 and associated to the functional categories by Ingenuity Pathway Analysis (IPA®, Qiagen; Bioinformatics, Redwood City, CA, USA) and significantly enriched in the list of 410 genes commonly amplified in the four cases. The most enriched categories were “Cell movement” and “Cell migration” (both P < 0.001). See also Additional file 2: Table S6 for gene overlapping between the two pathways. For the entire name of the genes, reported as gene ID, see Additional file 2: Table S5

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