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Table 5 Cox univariate and multivariate analyses of the prognostic factors related to overall survival (OS) for the patients with postradiation nasopharyngeal necrosis

From: A curative-intent endoscopic surgery for postradiation nasopharyngeal necrosis in patients with nasopharyngeal carcinoma

Clinical characteristic 2-year OS rate (%) Univariate analysis Multivariate analysis
P value HR (95% CI) P value HR (95% CI)
Gender   0.601 1.295 (0.491–3.412)   
 Female 84.0     
 Male 76.0     
Age (years)   0.331 1.589 (0.625–4.039)   
 < 51  84.7     
 ≥ 51 72.7     
Cycles of radiotherapy   0.717 1.197 (0.453–3.163)   
 One 80.8     
 Two 71.9     
Necrosis-free interval   0.617 1.372 (0.397–4.737)   
 Acute necrosis 86.3     
 Chronic necrosis 75.7     
Carotid artery exposure   0.817 1.122 (0.423–2.975)   
 Yes 68.6     
 No 82.1     
Osteoradionecrosis   0.607 0.782 (0.308–1.991)   
 Yes 81.2     
 No 71.4     
Postoperative pathological result   0.001 5.026 (1.974–12.799) 0.001 5.018 (1.970–12.782)
 Negative 88.4     
 Positive 54.2     
Status of the flap   0.055 2.467 (0.982–6.195) 0.056 2.442 (0.978–6.099)
 Survived 80.3     
 Necrotized 68.8     
  1. OS overall survival, HR hazard ratio, CI confidence interval