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Table 4 Predictors of nasopharyngeal defect re-epithelialization of patients with postradiation nasopharyngeal necrosis but with negative pathology for tumor recurrence at the time of surgery

From: A curative-intent endoscopic surgery for postradiation nasopharyngeal necrosis in patients with nasopharyngeal carcinoma

Clinical characteristic Total [cases (%)] Status of the re-epithelialization [cases (%)] Univariate logistic regression analysis
Survived Necrotized P-value OR (95% CI)
Gender     0.232 2.444 (0.565–10.570)
 Female 13 (25.0) 9 (21.4) 4 (40)   
 Male 39 (75.0) 33 (78.6) 6 (60)   
Age (years)     0.405 0.551 (0.135–2.241)
 < 51 25 (48.1) 19 (45.2) 6 (60)   
 ≥ 51 27 (51.9) 23 (54.8) 4 (40)   
Cycles of radiotherapy     0.022 5.500 (1.272–23.782)
 One 37 (71.2) 33 (78.6) 4 (40)   
 Two 15 (28.8) 9 (21.4) 6 (60)   
Necrosis-free interval     0.296 3.194 (0.362–28.180)
 Acute necrosis 12 (23.1) 11 (26.2) 1 (10)   
 Chronic necrosis 40 (76.9) 31 (73.8) 9 (90)   
Carotid artery exposure     0.978 0.980 (0.240–4.004)
 Yes 31 (56.9) 25 (59.5) 6 (60)   
 No 21 (40.4) 17 (40.5) 4 (40)   
Osteoradionecrosis     0.173 4.500 (0.517–39.149)
 Yes 37 (71.2) 28 (66.7) 9 (90)   
 No 15 (28.8) 14 (33.3) 1 (10)   
Status of the flap     < 0.001 180.000 (14.672–2208.254)
 Survived 41 (78.8) 40 (95.2) 1 (10)   
 Necrotized 11 (21.2) 2 (4.8) 9 (90)   
  1. OR odds ratio, CI confidence interval