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Fig. 3 | Cancer Communications

Fig. 3

From: DUXAP8, a pseudogene derived lncRNA, promotes growth of pancreatic carcinoma cells by epigenetically silencing CDKN1A and KLF2

Fig. 3

The silencing of DUXAP8 inhibited PC growth in vivo. a BxPC-3 cells with stable DUXAP8 knockdown were used for the in vivo study. Nude mice carrying tumors from respective groups are shown. b Tumor volumes were calculated after injection every 3 days. c Tumor weights from two groups are represented. d Images of HE staining and immunohistochemistry of the xenograft tumors. Representative Ki-67 protein levels in xenograft tumors as evaluated by IHC. Representative images and data based on three independent experiments. e qPCR was performed to detect the average expression of DUXAP8 in xenograft tumors (n = 6). Bars: s.d, *P < 0.05, **P < 0.01

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