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Fig. 1 | Cancer Communications

Fig. 1

From: DUXAP8, a pseudogene derived lncRNA, promotes growth of pancreatic carcinoma cells by epigenetically silencing CDKN1A and KLF2

Fig. 1

Relative expression of DUXAP8 in pancreatic cancer tissues and its clinical significance. a Hierarchical clustering analysis of differentially expressed lncRNAs (fold change > 2; P < 0.05) in pancreatic cancer and normal tissues. b Overlap of dysregulated lncRNAs in three GEO datasets. c The DUXAP8 gene is located at the chromosomal locus 22q11.1 and encodes a 2107-bp transcript ( d Relative expression of DUXAP8 in pancreatic cancer tissues compared with paired adjacent normal tissues (n = 58), and DUXAP8 expression was classified into two groups. e DUXAP8 expression was significantly higher in patients with a larger tumor size and a more advanced pathological stage (shown as ΔCT). f Patients with high DUXAP8 expression had significantly shorter overall survival than patients with low DUXAP8 expression (P < 0.001, log rank test). Bars: s.d., *P < 0.05, **P < 0.01

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