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Table 1 Demographic and baseline characteristics of patients with NPC who were treated with famitinib

From: Famitinib in combination with concurrent chemoradiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma: a phase 1, open-label, dose-escalation Study

Variables

Patients (n = 20)

Age, years

 Median (IQR)

43 (39–48)

 Range

26–56

 Male sex

18 (80%)

ECOG

 0

1 (5%)

 1

19 (95%)

 Histology, WHO type III

20 (100%)

Tumour stage

 T1

1 (5%)

 T2

3 (15%)

 T3

13 (65%)

 T4

3 (15%)

Node stage

 N1

2 (10%)

 N2

13 (65%)

 N3

5 (25%)

Clinical stage

 III

12 (60%)

 IVa

3 (15%)

 IVb

5 (25%)

EBV DNA,

 ≥ 4000 copy/ml

10 (50%)

VCA-IgA

 ≥ 1:80

15 (75%)

EA-IgA

 ≥ 1:10

13 (65%)

Smokinga

 Yes

9 (45%)

Family history of NPC

 Yes

3 (15%)

  1. ECOG Eastern Cooperative Oncology Group, WHO World Health Organization, EBV DNA Epstein–Barr virus DNA, VCA viral capsid antigen, IgA immunoglobulin A, EA, early antigen, NPC nasopharyngeal carcinoma
  2. aDefined as smoking ≥100 cigarettes/lifetime