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Table 4 Correlation response of MiniPDX versus PDX assays in PDX models

From: Characterization of drug responses of mini patient-derived xenografts in mice for predicting cancer patient clinical therapeutic response

 

Response in PDX

R

NR

Total

Response in Mini-PDX

 R

12

1

13

 NR

3

13

16

 Total

15

14

29

Positive predictive value

  

92%

Negative predictive value

  

81%

Sensitivity

  

80%

Specificity

  

93%

  1. R: responder; NR: non-responder