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Table 1 Drug preparations and treatment details

From: Characterization of drug responses of mini patient-derived xenografts in mice for predicting cancer patient clinical therapeutic response

Drug Supplier Preparationa PDX assayb MiniPDX assayb
S-1 Hengrui 0.5% HPMC + 0.2% Tween 80 10 mg/kg, po, qd*5/w 10 mg/kg, po, qd*5
Docetaxel DEMO 5% Tween 80 + 5% Ethanol + 90% Saline 20 mg/kg, ip, q4d 20 mg/kg, ip, q4d*2
Gemzar Eli Lilly Saline 60 mg/kg, ip, q4d 60 mg/kg, ip, q4d*2
Oxaliplatin Hengrui 5% Glucose 5 mg/kg, ip, biw 5 mg/kg, ip, q4d*2
Irinotecan DEMO 5% DMSO + 95% Saline 40 mg/kg, ip, q4d 50 mg/kg, ip, q4d*2
Cisplatin Hansoh Saline 5 mg/kg, ip, qw 5 mg/kg, ip, q4d*2
Epirubicin Pfizer Saline 5 mg/kg, ip, qw 5 mg/kg, ip, q4d*2
Capecitabine Adamas 0.5% HPMC + 0.2% Tween 80 400 mg/kg, po, qd*14 400 mg/kg, po, qd*7
5-FU Xudong-Haipu Saline 25 mg/kg, ip, qd*5/w 25 mg/kg, ip, qd*5
Erlotinib Topscience 0.5% HPMC + 0.2% Tween 80 50 mg/kg, po, qd 50 mg/kg, po, qd*7
Crizotinib Aladdin 0.5% HPMC + 0.2% Tween 80 50 mg/kg, po, qd 50 mg/kg, po, qd*7
AZD9291 Topscience 0.5% HPMC + 0.2% Tween 80 5 mg/kg, po, qd 5 mg/kg, po, qd*7
  1. po oral, ip intraperitoneal, qd once a day, biw twice a week, qw once a week, q4d once every 4 days
  2. a Recipe of formulation
  3. b Dose, dosing route, dosing frequency followed by, where indicated, dosing times and/or treatment duration