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Table 3 Multivariate analysis of patients from the Sun Yat-sen University Cancer Center

From: External validity of a prognostic nomogram for locoregionally advanced nasopharyngeal carcinoma based on the 8th edition of the AJCC/UICC staging system: a retrospective cohort study

  HR (95% CI) P-value
Factors included in the best predictive model
 The 8th AJCC/UICC N-classification 1.968 (1.480–2.617) < 0.001
 Age (per year increase) 1.055 (1.032–1.079) < 0.001
 GTVp (per cc increase) 1.016 (1.009–1.023) < 0.001
 LDH (per IU/L increase) 1.005 (1.000–1.010) 0.033
 BMI (per kg/m2 increase) 0.921 (0.854–0.995) 0.036
Factors absent from the best predictive model
 The 8th AJCC/UICC T-classification 1.076 (0.720–1.607) 0.721
 EBV DNA (< 103/103–104/104–105/105–106/≥ 106) 1.033 (0.826–1.293) 0.774
 Sex 0.759 (0.430–1.337) 0.339
 Histology 0.714 (0.305–1.671) 0.437
  1. HR hazard ratio, CI confidence interval, AJCC American Joint Committee on Cancer, UICC Union for International Cancer Control, GTVp gross primary tumor volume, LDH lactate dehydrogenase, BMI body mass index