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Table 1 Univariate and multivariate survival analysis of 90 GC patients

From: DDIT4 promotes gastric cancer proliferation and tumorigenesis through the p53 and MAPK pathways

Variable

Univariate log rank survival analysis

Multivariate Cox survival analysis

RR

95% CI

P value

RR

95% CI

P value

Age (years)

 < 60

1.000

     

 ≥ 60

1.085

0.832–1.413

0.547

   

Gender

 Male

1.000

     

 Female

1.091

0.797–1.494

0.588

   

Tumor size (cm)

 < 5

1.000

     

 ≥ 5

1.182

1.036–1.349

0.013

1.387

0.827–2.325

0.215

Invasion depth

 T1/2

1.000

     

 T3/4

1.610

1.098–2.360

0.015

1.496

0.696–3.216

0.302

Lymphatic metastasis

 N0

1.000

     

 N1–3

1.369

1.056–1.774

0.018

1.093

0.456–2.621

0.842

Distant metastasis

 M0

1.000

     

 M1

1.468

1.268–1.299

< 0.001

4.364

1.830–10.409

0.001

AJCC stage

 I/II

1.000

     

 III/IV

1.500

1.214–1.853

< 0.001

1.755

0.768–4.011

0.183

Pathological grade

 I/II

1.000

     

 III/IV

1.912

1.125–3.250

0.017

2.077

0.863–4.996

0.103

DDIT4 expression

 Low

1.000

     

 High

3.583

2.345–4.271

0.146

   
  1. RR risk ratio, 95% CI 95% confidence interval, AJCC American Joint Committee on Cancer