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Fig. 4 | Cancer Communications

Fig. 4

From: DDIT4 promotes gastric cancer proliferation and tumorigenesis through the p53 and MAPK pathways

Fig. 4

DDIT4 depletion inhibited GC xenograft tumor growth in vivo. a BGC823 cells stably expressing si-DDIT4 or scrambled control siRNA were subcutaneously injected into nude mice. DDIT4-silenced BGC823 cells formed smaller tumors compared with cells expressing the scrambled control after 4 weeks. b Tumor growth curves. c Representative images of xenograft tumors. d Tumor weight. e DDIT4 expression in xenograft tumors was determined by western blot. f HE and immunohistochemical staining for DDIT4 and Ki67 in xenograft tumors. ***P < 0.001, **P < 0.01, *P < 0.05

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