TY - JOUR AU - Sun, W. AU - Yan, L. PY - 2016 DA - 2016// TI - Gastric cancer: current and evolving treatment landscape JO - Chin J Cancer VL - 35 UR - https://doi.org/10.1186/s40880-016-0147-6 DO - 10.1186/s40880-016-0147-6 ID - Sun2016 ER - TY - JOUR AU - Crew, K. D. AU - Neugut, A. I. PY - 2006 DA - 2006// TI - Epidemiology of gastric cancer JO - World J Gastroenterol VL - 12 UR - https://doi.org/10.3748/wjg.v12.i3.354 DO - 10.3748/wjg.v12.i3.354 ID - Crew2006 ER - TY - JOUR AU - Bass, A. J. AU - Thorsson, V. AU - Shmulevich, I. AU - Reynolds, S. M. AU - Miller, M. AU - Bernard, B. PY - 2014 DA - 2014// TI - Comprehensive molecular characterization of gastric adenocarcinoma JO - Nature VL - 513 UR - https://doi.org/10.1038/nature13480 DO - 10.1038/nature13480 ID - Bass2014 ER - TY - JOUR AU - Ellisen, L. W. AU - Ramsayer, K. D. AU - Johannessen, C. M. AU - Yang, A. AU - Beppu, H. AU - Minda, K. PY - 2002 DA - 2002// TI - REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species JO - Mol Cell VL - 10 UR - https://doi.org/10.1016/S1097-2765(02)00706-2 DO - 10.1016/S1097-2765(02)00706-2 ID - Ellisen2002 ER - TY - JOUR AU - DeYoung, M. P. AU - Horak, P. AU - Sofer, A. AU - Sgroi, D. AU - Ellisen, L. W. PY - 2008 DA - 2008// TI - Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling JO - Genes Dev VL - 22 UR - https://doi.org/10.1101/gad.1617608 DO - 10.1101/gad.1617608 ID - DeYoung2008 ER - TY - JOUR AU - Barakat, D. J. AU - Mendonca, J. AU - Barberi, T. AU - Zhang, J. AU - Kachhap, S. K. AU - Paz-Priel, I. PY - 2016 DA - 2016// TI - C/EBPbeta regulates sensitivity to bortezomib in prostate cancer cells by inducing REDD1 and autophagosome-lysosome fusion JO - Cancer Lett VL - 375 UR - https://doi.org/10.1016/j.canlet.2016.03.005 DO - 10.1016/j.canlet.2016.03.005 ID - Barakat2016 ER - TY - JOUR AU - Wang, Y. AU - Han, E. AU - Xing, Q. AU - Yan, J. AU - Arrington, A. AU - Wang, C. PY - 2015 DA - 2015// TI - Baicalein upregulates DDIT4 expression which mediates mTOR inhibition and growth inhibition in cancer cells JO - Cancer Lett VL - 358 UR - https://doi.org/10.1016/j.canlet.2014.12.033 DO - 10.1016/j.canlet.2014.12.033 ID - Wang2015 ER - TY - JOUR AU - Gordon, M. A. AU - D’Amato, N. C. AU - Gu, H. AU - Babbs, B. AU - Wulfkuhle, J. AU - Petricoin, E. F. PY - 2017 DA - 2017// TI - Synergy between androgen receptor antagonism and inhibition of mTOR and HER2 in breast cancer JO - Mol Cancer Ther VL - 16 UR - https://doi.org/10.1158/1535-7163.MCT-17-0111 DO - 10.1158/1535-7163.MCT-17-0111 ID - Gordon2017 ER - TY - JOUR AU - Rehan, M. PY - 2017 DA - 2017// TI - An anti-cancer drug candidate OSI-027 and its analog as inhibitors of mTOR: computational insights into the inhibitory mechanisms JO - J Cell Biochem VL - 118 UR - https://doi.org/10.1002/jcb.26117 DO - 10.1002/jcb.26117 ID - Rehan2017 ER - TY - JOUR AU - Molitoris, J. K. AU - McColl, K. S. AU - Swerdlow, S. AU - Matsuyama, M. AU - Lam, M. AU - Finkel, T. H. PY - 2011 DA - 2011// TI - Glucocorticoid elevation of dexamethasone-induced gene 2 (Dig2/RTP801/REDD1) protein mediates autophagy in lymphocytes JO - J Biol Chem VL - 286 UR - https://doi.org/10.1074/jbc.M111.245423 DO - 10.1074/jbc.M111.245423 ID - Molitoris2011 ER - TY - JOUR AU - Jia, W. AU - Chang, B. AU - Sun, L. AU - Zhu, H. AU - Pang, L. AU - Tao, L. PY - 2014 DA - 2014// TI - REDD1 and p-AKT over-expression may predict poor prognosis in ovarian cancer JO - Int J Clin Exp Pathol VL - 7 ID - Jia2014 ER - TY - JOUR AU - Pinto, J. A. AU - Rolfo, C. AU - Raez, L. E. AU - Prado, A. AU - Araujo, J. M. AU - Bravo, L. PY - 2017 DA - 2017// TI - In silico evaluation of DNA damage inducible transcript 4 gene (DDIT4) as prognostic biomarker in several malignancies JO - Sci Rep VL - 7 UR - https://doi.org/10.1038/s41598-017-01207-3 DO - 10.1038/s41598-017-01207-3 ID - Pinto2017 ER - TY - JOUR AU - Evan, G. I. AU - Vousden, K. H. PY - 2001 DA - 2001// TI - Proliferation, cell cycle and apoptosis in cancer JO - Nature VL - 411 UR - https://doi.org/10.1038/35077213 DO - 10.1038/35077213 ID - Evan2001 ER - TY - JOUR AU - Kalisperati, P. AU - Spanou, E. AU - Pateras, I. S. AU - Korkolopoulou, P. AU - Varvarigou, A. AU - Karavokyros, I. PY - 2017 DA - 2017// TI - Inflammation, DNA damage, Helicobacter pylori and gastric tumorigenesis JO - Front Genet VL - 8 UR - https://doi.org/10.3389/fgene.2017.00020 DO - 10.3389/fgene.2017.00020 ID - Kalisperati2017 ER - TY - JOUR AU - Coussens, L. M. AU - Werb, Z. PY - 2002 DA - 2002// TI - Inflammation and cancer JO - Nature VL - 420 UR - https://doi.org/10.1038/nature01322 DO - 10.1038/nature01322 ID - Coussens2002 ER - TY - JOUR AU - Negrini, S. AU - Gorgoulis, V. G. AU - Halazonetis, T. D. PY - 2010 DA - 2010// TI - Genomic instability—an evolving hallmark of cancer JO - Nat Rev Mol Cell Biol VL - 11 UR - https://doi.org/10.1038/nrm2858 DO - 10.1038/nrm2858 ID - Negrini2010 ER - TY - JOUR AU - Luo, J. AU - Solimini, N. L. AU - Elledge, S. J. PY - 2009 DA - 2009// TI - Principles of cancer therapy: oncogene and non-oncogene addiction JO - Cell VL - 136 UR - https://doi.org/10.1016/j.cell.2009.02.024 DO - 10.1016/j.cell.2009.02.024 ID - Luo2009 ER - TY - JOUR AU - Zhou, X. AU - Liu, W. AU - Hu, X. AU - Dorrance, A. AU - Garzon, R. AU - Houghton, P. J. PY - 2017 DA - 2017// TI - Regulation of CHK1 by mTOR contributes to the evasion of DNA damage barrier of cancer cells JO - Sci Rep VL - 7 UR - https://doi.org/10.1038/s41598-017-01729-w DO - 10.1038/s41598-017-01729-w ID - Zhou2017 ER - TY - JOUR AU - Hwang-Verslues, W. W. AU - Chang, P. H. AU - Wei, P. C. AU - Yang, C. Y. AU - Huang, C. K. AU - Kuo, W. H. PY - 2011 DA - 2011// TI - miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1 JO - Oncogene VL - 30 UR - https://doi.org/10.1038/onc.2010.618 DO - 10.1038/onc.2010.618 ID - Hwang-Verslues2011 ER - TY - JOUR AU - Jin, H. O. AU - Seo, S. K. AU - Woo, S. H. AU - Kim, Y. S. AU - Hong, S. E. AU - Yi, J. Y. PY - 2011 DA - 2011// TI - Redd1 inhibits the invasiveness of non-small cell lung cancer cells JO - Biochem Biophys Res Commun VL - 407 UR - https://doi.org/10.1016/j.bbrc.2011.03.047 DO - 10.1016/j.bbrc.2011.03.047 ID - Jin2011 ER - TY - JOUR AU - Yun, S. M. AU - Woo, S. H. AU - Oh, S. T. AU - Hong, S. E. AU - Choe, T. B. AU - Ye, S. K. PY - 2016 DA - 2016// TI - Melatonin enhances arsenic trioxide-induced cell death via sustained upregulation of Redd1 expression in breast cancer cells JO - Mol Cell Endocrinol VL - 422 UR - https://doi.org/10.1016/j.mce.2015.11.016 DO - 10.1016/j.mce.2015.11.016 ID - Yun2016 ER - TY - JOUR AU - Iakoucheva, L. M. AU - Radivojac, P. AU - Brown, C. J. AU - O’Connor, T. R. AU - Sikes, J. G. AU - Obradovic, Z. PY - 2004 DA - 2004// TI - The importance of intrinsic disorder for protein phosphorylation JO - Nucleic Acids Res VL - 32 UR - https://doi.org/10.1093/nar/gkh253 DO - 10.1093/nar/gkh253 ID - Iakoucheva2004 ER - TY - JOUR AU - Yoshida, T. AU - Mett, I. AU - Bhunia, A. K. AU - Bowman, J. AU - Perez, M. AU - Zhang, L. PY - 2010 DA - 2010// TI - Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema JO - Nat Med VL - 16 UR - https://doi.org/10.1038/nm.2157 DO - 10.1038/nm.2157 ID - Yoshida2010 ER - TY - JOUR AU - Dennis, M. D. AU - Coleman, C. S. AU - Berg, A. AU - Jefferson, L. S. AU - Kimball, S. R. PY - 2014 DA - 2014// TI - REDD1 enhances protein phosphatase 2A-mediated dephosphorylation of Akt to repress mTORC1 signaling JO - Sci Signal VL - 7 UR - https://doi.org/10.1126/scisignal.2005103 DO - 10.1126/scisignal.2005103 ID - Dennis2014 ER - TY - JOUR AU - Horak, P. AU - Crawford, A. R. AU - Vadysirisack, D. D. AU - Nash, Z. M. AU - DeYoung, M. P. AU - Sgroi, D. PY - 2010 DA - 2010// TI - Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis JO - Proc Natl Acad Sci USA VL - 107 UR - https://doi.org/10.1073/pnas.0907705107 DO - 10.1073/pnas.0907705107 ID - Horak2010 ER - TY - JOUR AU - Wagner, E. F. AU - Nebreda, A. R. PY - 2009 DA - 2009// TI - Signal integration by JNK and p38 MAPK pathways in cancer development JO - Nat Rev Cancer VL - 9 UR - https://doi.org/10.1038/nrc2694 DO - 10.1038/nrc2694 ID - Wagner2009 ER - TY - JOUR AU - Deng, C. AU - Zhang, P. AU - Harper, J. W. AU - Elledge, S. J. AU - Leder, P. PY - 1995 DA - 1995// TI - Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control JO - Cell VL - 82 UR - https://doi.org/10.1016/0092-8674(95)90039-X DO - 10.1016/0092-8674(95)90039-X ID - Deng1995 ER - TY - JOUR AU - Tibbetts, R. S. AU - Brumbaugh, K. M. AU - Williams, J. M. AU - Sarkaria, J. N. AU - Cliby, W. A. AU - Shieh, S. Y. PY - 1999 DA - 1999// TI - A role for ATR in the DNA damage-induced phosphorylation of p53 JO - Genes Dev VL - 13 UR - https://doi.org/10.1101/gad.13.2.152 DO - 10.1101/gad.13.2.152 ID - Tibbetts1999 ER - TY - JOUR AU - Miyashita, T. AU - Reed, J. C. PY - 1995 DA - 1995// TI - Tumor suppressor p53 is a direct transcriptional activator of the human bax gene JO - Cell VL - 80 UR - https://doi.org/10.1016/0092-8674(95)90412-3 DO - 10.1016/0092-8674(95)90412-3 ID - Miyashita1995 ER -