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Table 5 Frequencies of coding SNVs in MEFs exposed to ionizing radiation

From: Lower genomic stability of induced pluripotent stem cells reflects increased non-homologous end joining

# Locus Gene Mutation Amino acid change Freq. IR− (%) Freq. IR+ (%)
1 Chr1:174406441 Slamf9 T−>C M−>T 0.0 23.68
2 Chr2:10014034 Kin G−>A E−>K 0.0 20.00
3 Chr4:120619977 Zfp69 A−>G S−>P 0.0 20.00
4 Chr4:146162835 Zfp600 T−>A I−>K 0.0 20.00
5 Chr5:72655729 Atp10d C−>G P−>R 0.0 27.78
6 Chr7:25371714 Zfp575 G−>A A−>V 0.0 25.00
7 Chr7:31658366 Cd22 C−>T R−>Q 0.0 30.56
8 Chr7:48249435 4930433I11Rik A−>T D−>V 0.0 23.08
9 Chr7:48249440 4930433I11Rik G−>C A−>P 0.0 24.00
10 Chr8:93611040 Rbl2 G−>C R−>T 0.0 20.83
11 Chr14:52076074 Vmn2r89 C−>T A−>V 0.0 20.00
12 Chr18:67019622 Mc4r C−>T G−>S 0.0 22.50
13 Chr18:70668975 Poli C−>T G−>R 0.0 29.03
  1. IR− control cells not irradiated, IR+ irradiated cells, SNV single-nucleotide variants