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Table 4 Frequencies of coding SNVs in ESCs exposed to ionizing radiation

From: Lower genomic stability of induced pluripotent stem cells reflects increased non-homologous end joining

# Locus Gene Mutation Amino acid change Freq. IR− (%) Freq. IR+ (%)
1 Chr1:46244148 Dnahc7b T−> C V−>A 0.0 28.57
2 Chr1:172987924 Fcgr3 A−>C S−>A 0.0 30
3 Chr2:180330052 Ogfr A−>G E−>G 0.0 22.06
4 Chr8:22465823 Defa-rs1 C−>G R−>P 0.0 20
5 Chr10:80640826 Eef2 G−>A E−>K 0.0 30.11
6 Chr15:77465439 Apol11b C−>A K−>N 0.0 20
7 chrX:131293286 Armcx3 G−>A C−>Y 0.0 21.62
  1. IR− control cells not irradiated, IR+ irradiated cells, SNV single-nucleotide variants