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Table 4 Frequencies of coding SNVs in ESCs exposed to ionizing radiation

From: Lower genomic stability of induced pluripotent stem cells reflects increased non-homologous end joining

#

Locus

Gene

Mutation

Amino acid change

Freq. IR− (%)

Freq. IR+ (%)

1

Chr1:46244148

Dnahc7b

T−> C

V−>A

0.0

28.57

2

Chr1:172987924

Fcgr3

A−>C

S−>A

0.0

30

3

Chr2:180330052

Ogfr

A−>G

E−>G

0.0

22.06

4

Chr8:22465823

Defa-rs1

C−>G

R−>P

0.0

20

5

Chr10:80640826

Eef2

G−>A

E−>K

0.0

30.11

6

Chr15:77465439

Apol11b

C−>A

K−>N

0.0

20

7

chrX:131293286

Armcx3

G−>A

C−>Y

0.0

21.62

  1. IR− control cells not irradiated, IR+ irradiated cells, SNV single-nucleotide variants
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Cancer Communications

ISSN: 2523-3548

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