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Table 3 Summary of somatic mutations in each cell line

From: Lower genomic stability of induced pluripotent stem cells reflects increased non-homologous end joining

 

lv-iPSCs

ESCs

MEFs

Somatic mutation

92,027

789

2403

 CDS

867

15

24

 Intergenic

54,086

570

1526

 Intron

35,567

173

694

 5′ UTR

5128

22

106

 3′ UTR

1379

9

53

 Splice site

0

0

0

CDS

867

15

24

 Synonymous

559

8

11

 Nonsynonymous

307

7

13

 Nonsense

1

0

0

  1. CDS coding sequence, indel insertion or deletion, UTR untranslated region